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MeSH Review

Trigeminal Neuralgia

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Disease relevance of Trigeminal Neuralgia


Psychiatry related information on Trigeminal Neuralgia


High impact information on Trigeminal Neuralgia


Chemical compound and disease context of Trigeminal Neuralgia


Biological context of Trigeminal Neuralgia


Anatomical context of Trigeminal Neuralgia


Gene context of Trigeminal Neuralgia

  • Our results demonstrated that the myelin sheaths of schwann cell from the peripheral neuroectomy of trigeminal neuralgia were positively expressing mRNA of BMP-2, 3, 4 and 5 [22].
  • Seventy-eight patients with tic douloureux who underwent 92 percutaneous radiofrequency trigeminal gangliolysis (PRTG) procedures were evaluated on average of 56 months postoperatively [23].
  • We conclude that in MS trigeminal neuralgia is usually caused by demyelinating lesions affecting pontine trigeminal pathways [24].
  • Additional trials are necessary to conclusively evaluate the efficacy of NMDA-receptor antagonists in trigeminal neuralgia [25].
  • MATERIALS AND METHODS: Thirteen patients with unilateral trigeminal neuralgia and 50 control subjects underwent three-dimensional fast inflow with steady-state precession (FISP) and contrast material-enhanced magnetization-prepared rapid acquisition gradient-echo (MP-RAGE) MR imaging [17].

Analytical, diagnostic and therapeutic context of Trigeminal Neuralgia


  1. Carbamazepine-induced syndrome of inappropriate antidiuretic hormone secretion. Reversal by concomitant phenytoin therapy. Sordillo, P., Sagransky, D.M., Mercado, R.M., Michelis, M.F. Arch. Intern. Med. (1978) [Pubmed]
  2. Gabapentin relieves trigeminal neuralgia in multiple sclerosis patients. Khan, O.A. Neurology (1998) [Pubmed]
  3. An open-label trial of gabapentin treatment of paroxysmal symptoms in multiple sclerosis patients. Solaro, C., Lunardi, G.L., Capello, E., Inglese, M., Messmer Uccelli, M., Uccelli, A., Mancardi, G.L. Neurology (1998) [Pubmed]
  4. Preventative effect of repeated nasal applications of capsaicin in cluster headache. Fusco, B.M., Marabini, S., Maggi, C.A., Fiore, G., Geppetti, P. Pain (1994) [Pubmed]
  5. Relief of cluster-tic syndrome by the combination of lithium and carbamazepine. Pascual, J., Berciano, J. Cephalalgia : an international journal of headache. (1993) [Pubmed]
  6. Oxcarbazepine. A review of its pharmacology and therapeutic potential in epilepsy, trigeminal neuralgia and affective disorders. Grant, S.M., Faulds, D. Drugs (1992) [Pubmed]
  7. Treatment of tic douloureux by percutaneous retrogasserian glycerol injection. Lunsford, L.D. JAMA (1982) [Pubmed]
  8. Management of trigeminal neuralgia (tic douloureux). Voorhies, R., Patterson, R.H. JAMA (1981) [Pubmed]
  9. Letter: Alcohol injection for trigeminal neuralgia. Ecker, A. JAMA (1975) [Pubmed]
  10. Dopaminergic effects of carbamazepine. Relationship to clinical response in affective illness. Post, R.M., Rubinow, D.R., Uhde, T.W., Ballenger, J.C., Linnoila, M. Arch. Gen. Psychiatry (1986) [Pubmed]
  11. Baclofen in the treatment of trigeminal neuralgia: double-blind study and long-term follow-up. Fromm, G.H., Terrence, C.F., Chattha, A.S. Ann. Neurol. (1984) [Pubmed]
  12. A placebo-controlled trial of lamotrigine for painful HIV-associated neuropathy. Simpson, D.M., Olney, R., McArthur, J.C., Khan, A., Godbold, J., Ebel-Frommer, K. Neurology (2000) [Pubmed]
  13. Gabapentin for idiopathic trigeminal neuralgia: report of two cases. Sist, T., Filadora, V., Miner, M., Lema, M. Neurology (1997) [Pubmed]
  14. Pimozide therapy for trigeminal neuralgia. Ecker, A. Arch. Neurol. (1990) [Pubmed]
  15. Percutaneous retrogasserian glycerol rhizotomy for tic douloureux: Part 2. Results nd implications of trigeminal evoked potential studies. Bennett, M.H., Lunsford, L.D. Neurosurgery (1984) [Pubmed]
  16. Effects of dextropropoxyphene on the steady-state kinetics of oxcarbazepine and its metabolites. Mogensen, P.H., Jórgensen, L., Boas, J., Dam, M., Vesterager, A., Flesch, G., Jensen, P.K. Acta neurologica Scandinavica. (1992) [Pubmed]
  17. Trigeminal neuralgia: comparison of two MR imaging techniques in the demonstration of neurovascular contact. Majoie, C.B., Hulsmans, F.J., Verbeeten, B., Castelijns, J.A., van Beek, E.J., Valk, J., Bosch, D.A. Radiology. (1997) [Pubmed]
  18. The analgesic effect of tocainide in trigeminal neuralgia. Lindström, P., Lindblom, U. Pain (1987) [Pubmed]
  19. Effects of D-baclofen and L-baclofen on the trigeminal nucleus. Fromm, G.H., Shibuya, T., Nakata, M., Terrence, C.F. Neuropharmacology (1990) [Pubmed]
  20. Autonomic and histopathological effects of percutaneous trigeminal ganglion compression in the rabbit. Preul, M.C., Long, P.B., Brown, J.A., Velasco, M.E., Weaver, M.T. J. Neurosurg. (1990) [Pubmed]
  21. Cerebrospinal fluid neuropeptides and monoaminergic transmitters in patients with trigeminal neuralgia. Strittmatter, M., Grauer, M., Isenberg, E., Hamann, G., Fischer, C., Hoffmann, K.H., Blaes, F., Schimrigk, K. Headache. (1997) [Pubmed]
  22. Transcriptional mRNA of bone morphogenetic proteins 2, 3, 4, and 5 in trigeminal nerve, benign and malignant peripheral nerve sheath tumors. Tang, C.S., Jin, Y., Cheng, K.I., Yu, K.L., Suwa, F., Nakatsuji, I., Makigusa, K., Fang, Y.R. The Kaohsiung journal of medical sciences. (2001) [Pubmed]
  23. Comparison of percutaneous radiofrequency gangliolysis and microvascular decompression for the surgical management of tic douloureux. Burchiel, K.J., Steege, T.D., Howe, J.F., Loeser, J.D. Neurosurgery (1981) [Pubmed]
  24. Trigeminal neuralgia in patients with multiple sclerosis: lesion localization with magnetic resonance imaging. Gass, A., Kitchen, N., MacManus, D.G., Moseley, I.F., Hennerici, M.G., Miller, D.H. Neurology (1997) [Pubmed]
  25. A randomized, controlled trial of high-dose dextromethorphan in facial neuralgias. Gilron, I., Booher, S.L., Rowan, M.S., Smoller, M.S., Max, M.B. Neurology (2000) [Pubmed]
  26. The effect of glycerol on autotomy. An experimental model of neuralgia pain. Rappaport, Z.H., Seltzer, Z., Zagzag, D. Pain (1986) [Pubmed]
  27. Tizanidine in the management of trigeminal neuralgia. Vilming, S.T., Lyberg, T., Lataste, X. Cephalalgia : an international journal of headache. (1986) [Pubmed]
  28. Identification of Meckel cave during percutaneous glycerol rhizotomy for tic douloureux. Lunsford, L.D. AJNR. American journal of neuroradiology. (1982) [Pubmed]
  29. Trigeminal Nerve-Blood Vessel Relationship as Revealed by High-resolution Magnetic Resonance Imaging and Its Effect on Pain Relief after Gamma Knife Radiosurgery for Trigeminal Neuralgia. Brisman, R., Khandji, A.G., Mooij, R.B. Neurosurgery (2002) [Pubmed]
  30. Pharmacotherapy of trigeminal neuralgia. Sindrup, S.H., Jensen, T.S. The Clinical journal of pain. (2002) [Pubmed]
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