Gene Review:
MC5R - melanocortin 5 receptor
Homo sapiens
Synonyms:
MC-2, MC5-R, Melanocortin receptor 5
- Expression, candidate gene, and population studies of the melanocortin 5 receptor. Hatta, N., Dixon, C., Ray, A.J., Phillips, S.R., Cunliffe, W.J., Dale, M., Todd, C., Meggit, S., Birch-MacHin, M.A., Rees, J.L. J. Invest. Dermatol. (2001)
- Melanocortin 5 receptor and ocular immunity. Taylor, A.W., Kitaichi, N., Biros, D. Cell. Mol. Biol. (Noisy-le-grand) (2006)
- The glycoprotein precursor gene of the attenuated Junin virus vaccine strain (Candid #1). Ghiringhelli, P.D., Albarino, C.G., Piboul, M., Romanowski, V. Am. J. Trop. Med. Hyg. (1997)
- Anticancer activities of orally administered menogaril against human stomach and breast cancers implanted in nude mice. Inaba, M., Sato, S., Yamori, T., Tashiro, T., Ohnishi, Y., Maruo, K., Ueyama, Y., Tsuruo, T. Anticancer Res. (1992)
- Lack of association between variations in the melanocortin 5 receptor gene and bipolar disorder. Lohoff, F.W., Berrettini, W.H. Psychiatr. Genet. (2005)
- Peripheral Effect of {alpha}-Melanocyte-stimulating Hormone on Fatty Acid Oxidation in Skeletal Muscle. An, J.J., Rhee, Y., Kim, S.H., Kim, D.M., Han, D.H., Hwang, J.H., Jin, Y.J., Cha, B.S., Baik, J.H., Lee, W.T., Lim, S.K. J. Biol. Chem. (2007)
- Targeting melanocortin receptors as potential novel therapeutics. Getting, S.J. Pharmacol. Ther. (2006)
- The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs. Klovins, J., Haitina, T., Fridmanis, D., Kilianova, Z., Kapa, I., Fredriksson, R., Gallo-Payet, N., Schiöth, H.B. Mol. Biol. Evol. (2004)
- Tissue transglutaminase expression in quail epiphyseal chondrocytes. Gionti, E., Sanchez, M., Arcella, A., Pontarelli, G., Tavassi, S., Gentile, V., Cozzolino, A., Porta, R. Cell Biol. Int. (1999)
- Effects of thymidine analogues on murine and human cells. Smellie, S.G., Parsons, P.G. The Australian journal of experimental biology and medical science. (1979)
- Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R. Balse-Srinivasan, P., Grieco, P., Cai, M., Trivedi, D., Hruby, V.J. J. Med. Chem. (2003)
- Localization of the human melanocortin-5 receptor gene (MC5R) to chromosome band 18p11.2 by fluorescence in situ hybridization. Chowdhary, B.P., Gustavsson, I., Wikberg, J.E., Chhajlani, V. Cytogenet. Cell Genet. (1995)
- Improving electrotransfection efficiency by post-pulse centrifugation. Li, L.H., Ross, P., Hui, S.W. Gene Ther. (1999)
- Molecular cloning, characterization and brain mapping of the melanocortin 5 receptor in the goldfish. Cerdá-Reverter, J.M., Ling, M.K., Schiöth, H.B., Peter, R.E. J. Neurochem. (2003)
- Melanocortin-5 receptor: a marker of human sebocyte differentiation. Zhang, L., Li, W.H., Anthonavage, M., Eisinger, M. Peptides (2006)
- Linkage and association studies between the melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the Québec Family Study. Chagnon, Y.C., Chen, W.J., Pérusse, L., Chagnon, M., Nadeau, A., Wilkison, W.O., Bouchard, C. Mol. Med. (1997)
- Evidence for direct actions of melanocortin peptides on bone metabolism. Dumont, L.M., Wu, C.S., Tatnell, M.A., Cornish, J., Mountjoy, K.G. Peptides (2005)
- Molecular cloning of a novel human melanocortin receptor. Chhajlani, V., Muceniece, R., Wikberg, J.E. Biochem. Biophys. Res. Commun. (1993)
- Phenylguanidines as selective nonpeptide melanocortin-5 receptor antagonists. Chen, C., Yu, J., Fleck, B.A., Hoare, S.R., Saunders, J., Foster, A.C. J. Med. Chem. (2004)
- ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin. Slominski, A., Ermak, G., Mihm, M. J. Clin. Endocrinol. Metab. (1996)
- Functional characterization of human neuropeptide Y receptor subtype five specific antagonists using a luciferase reporter gene assay. Beauverger, P., Rodriguez, M., Nicolas, J.P., Audinot, V., Lamamy, V., Dromaint, S., Nagel, N., Macia, C., Léopold, O., Galizzi, J.P., Caignard, D.H., Aldana, I., Monge, A., Chomarat, P., Boutin, J.A. Cell. Signal. (2005)
- Glutamine235 and arginine272 in human melanocortin 5 receptor determines its low affinity to MSH. Frändberg, P.A., Xu, X., Chhajlani, V. Biochem. Biophys. Res. Commun. (1997)
- Evidence for a stimulatory action of melanin-concentrating hormone on luteinising hormone release involving MCH1 and melanocortin-5 receptors. Murray, J.F., Hahn, J.D., Kennedy, A.R., Small, C.J., Bloom, S.R., Haskell-Luevano, C., Coen, C.W., Wilson, C.A. J. Neuroendocrinol. (2006)
- Biological and conformational study of beta-substituted prolines in MT-II template: steric effects leading to human MC5 receptor selectivity. Cai, M., Cai, C., Mayorov, A.V., Xiong, C., Cabello, C.M., Soloshonok, V.A., Swift, J.R., Trivedi, D., Hruby, V.J. J. Pept. Res. (2004)
- CRF and stress in fish. Flik, G., Klaren, P.H., Van den Burg, E.H., Metz, J.R., Huising, M.O. Gen. Comp. Endocrinol. (2006)
- Species-dependent pharmacological properties of the melanocortin-5 receptor. Huang, R.R., Singh, G., Van der Ploeg, L.H., Fong, T.M. J. Recept. Signal Transduct. Res. (2000)
- Thyrotropin releasing hormone (TRH) selectively binds and activates the melanocortin 1 receptor. Schiöth, H.B., Prusis, P., Muceniece, R., Mutulis, F., Mutule, I., Wikberg, J.E. Peptides (1999)
- Stimulation of intracellular free calcium in GH3 cells by gamma3-melanocyte-stimulating hormone. Involvement of a novel melanocortin receptor? Langouche, L., Roudbaraki, M., Pals, K., Denef, C. Endocrinology (2001)
- Characterization of the porcine melanocortin 2 receptor gene (MC2R ). Jacobs, K., Van Poucke, M., Mattheeuws, M., Chardon, P., Yerle, M., Rohrer, G., Van Zeveren, A., Peelman, L.J. Anim. Genet. (2002)
- The melanocortin 5 receptor is expressed in human sebaceous glands and rat preputial cells. Thiboutot, D., Sivarajah, A., Gilliland, K., Cong, Z., Clawson, G. J. Invest. Dermatol. (2000)