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Gene Review

IFT81  -  intraflagellar transport 81

Homo sapiens

Synonyms: CDV-1, CDV-1R, CDV1, CDV1R, Carnitine deficiency-associated protein expressed in ventricle 1, ...
 
 
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High impact information on IFT81

  • The splice sites conformed to the GT-AG rule, and the CDV-1R mRNA containing 19 exons was processed [1].
  • The CDV-1/1R gene was located close to DSMIT68 on mouse Chromosome (Chr) 5, corresponding to human Chr 12q24 [1].
  • Genomic organization and mapping of mouse CDV (carnitine deficiency-associated gene expressed in ventricle)-1 and its related CDV-1R gene [1].
  • Furthermore, we proved that the open reading frame of Cdv-1R/CDV-1R spans the exons 2 approximately 19 instead of exons 9 approximately 19; and the peptide encoded by CDV-1R was composed of 676 amino acids containing a putative signal peptide instead of 414 amino acids described previously [2].
  • Identification of human CDV-1R and mouse Cdv-1R, two novel proteins with putative signal peptides, especially highly expressed in testis and increased with the male sex maturation [2].
 

Associations of IFT81 with chemical compounds

  • In the present paper, the CDV-1/1R gene was isolated from a mouse genomic BAC library, and the genomic structure was characterized [1].
  • CDV 1 mg/kg was given three times per week intravenously with intravenous hydration and oral probenecid [3].

References

  1. Genomic organization and mapping of mouse CDV (carnitine deficiency-associated gene expressed in ventricle)-1 and its related CDV-1R gene. Higashi, M., Kobayashi, K., Iijima, M., Wakana, S., Horiuchi, M., Yasuda, T., Yoshida, G., Kanmura, Y., Saheki, T. Mamm. Genome (2000) [Pubmed]
  2. Identification of human CDV-1R and mouse Cdv-1R, two novel proteins with putative signal peptides, especially highly expressed in testis and increased with the male sex maturation. Peng, J., Yu, L., Horiuchi, M., Zhang, P., Huang, X., Zhang, Y., Li, D., Jalil, M.A., Zhao, S. Mol. Biol. Rep. (2002) [Pubmed]
  3. Disseminated adenovirus infection with respiratory failure in pediatric liver transplant recipients: impact of intravenous cidofovir and inhaled nitric oxide. Wallot, M.A., Dohna-Schwake, C., Auth, M., Nadalin, S., Fiedler, M., Malagó, M., Broelsch, C., Voit, T. Pediatric transplantation. (2006) [Pubmed]
 
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