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MeSH Review

Sexual Maturation

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Disease relevance of Sexual Maturation


Psychiatry related information on Sexual Maturation


High impact information on Sexual Maturation


Chemical compound and disease context of Sexual Maturation


Biological context of Sexual Maturation


Anatomical context of Sexual Maturation


Associations of Sexual Maturation with chemical compounds


Gene context of Sexual Maturation


Analytical, diagnostic and therapeutic context of Sexual Maturation


  1. Adult-onset idiopathic hypogonadotropic hypogonadism--a treatable form of male infertility. Nachtigall, L.B., Boepple, P.A., Pralong, F.P., Crowley, W.F. N. Engl. J. Med. (1997) [Pubmed]
  2. Hyperprolactinemia in girls with idiopathic precocious puberty under prolonged treatment with cyproterone acetate. Fonzo, D., Angeli, A., Sivieri, R., Andriolo, S., Frajria, R., Ceresa, F. J. Clin. Endocrinol. Metab. (1977) [Pubmed]
  3. The induction of antibodies to human luteinizing hormone by contaminated clinical pituitary hormone preparations. Burstein, S., Kaplan, S.L., Grumbach, M.M. J. Clin. Endocrinol. Metab. (1983) [Pubmed]
  4. Effect of prenatal alcohol exposure on sexual maturation of female rat offspring. Esquifino, A.I., Sanchis, R., Guerri, C. Neuroendocrinology (1986) [Pubmed]
  5. Plasma testosterone and dihydrotestosterone in male rats during sexual maturation and following orchidectomy and experimental bilateral cryptorchidism. Gupta, D., Zarzycki, J., Rager, K. Steroids (1975) [Pubmed]
  6. Validity of self-assessment of sexual maturation in adolescent male patients with cystic fibrosis. Boas, S.R., Falsetti, D., Murphy, T.D., Orenstein, D.M. The Journal of adolescent health : official publication of the Society for Adolescent Medicine. (1995) [Pubmed]
  7. Experimental diabetes has adverse effects on the differentiation of ventral prostate during sexual maturation of rats. Soudamani, S., Yuvaraj, S., Malini, T., Balasubramanian, K. The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology. (2005) [Pubmed]
  8. Use of a potent, long acting agonist of gonadotropin-releasing hormone in the treatment of precocious puberty. Boepple, P.A., Mansfield, M.J., Wierman, M.E., Rudlin, C.R., Bode, H.H., Crigler, J.F., Crawford, J.D., Crowley, W.F. Endocr. Rev. (1986) [Pubmed]
  9. Phenobarbital exposure in utero: alterations in female reproductive function in rats. Gupta, C., Sonawane, B.R., Yaffe, S.J., Shapiro, B.H. Science (1980) [Pubmed]
  10. Opioid peptides modulate luteinizing hormone secretion during sexual maturation. Blank, M.S., Panerai, A.E., Friesen, H.G. Science (1979) [Pubmed]
  11. Efficacy and safety of lovastatin in adolescent males with heterozygous familial hypercholesterolemia: a randomized controlled trial. Stein, E.A., Illingworth, D.R., Kwiterovich, P.O., Liacouras, C.A., Siimes, M.A., Jacobson, M.S., Brewster, T.G., Hopkins, P., Davidson, M., Graham, K., Arensman, F., Knopp, R.H., DuJovne, C., Williams, C.L., Isaacsohn, J.L., Jacobsen, C.A., Laskarzewski, P.M., Ames, S., Gormley, G.J. JAMA (1999) [Pubmed]
  12. Leuprorelin. A review of its pharmacology and therapeutic use in prostatic cancer, endometriosis and other sex hormone-related disorders. Plosker, G.L., Brogden, R.N. Drugs (1994) [Pubmed]
  13. Patho-physiologic findings after chronic tryptophan deficiency in rats: a model for delayed growth and aging. Segall, P.E., Timiras, P.S. Mech. Ageing Dev. (1976) [Pubmed]
  14. Effects of atrazine on sexual maturation in female Japanese quail induced by photostimulation or exogenous gonadotropin. Wilhelms, K.W., Cutler, S.A., Proudman, J.A., Anderson, L.L., Scanes, C.G. Environ. Toxicol. Chem. (2006) [Pubmed]
  15. Corticosterone administration to rat pups, but not maternal separation, affects sexual maturation and glucocorticoid receptor immunoreactivity in the testis. Biagini, G., Pich, E.M. Pharmacol. Biochem. Behav. (2002) [Pubmed]
  16. Neonatal hypothalamic c-fos expression in an excitotoxicity-induced model of precocious puberty. Smyth, C.E., Natarajan, M., Wilkinson, M. Brain Res. Dev. Brain Res. (1997) [Pubmed]
  17. Prepubertal increases in gonadotropin-releasing hormone mRNA, gonadotropin-releasing hormone precursor, and subsequent maturation of precursor processing in male rats. Dutlow, C.M., Rachman, J., Jacobs, T.W., Millar, R.P. J. Clin. Invest. (1992) [Pubmed]
  18. Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice. Jänne, P.A., Suchy, S.F., Bernard, D., MacDonald, M., Crawley, J., Grinberg, A., Wynshaw-Boris, A., Westphal, H., Nussbaum, R.L. J. Clin. Invest. (1998) [Pubmed]
  19. Pharmacokinetics of melatonin in human sexual maturation. Cavallo, A., Ritschel, W.A. J. Clin. Endocrinol. Metab. (1996) [Pubmed]
  20. Treatment of true precocious puberty with a potent luteinizing hormone-releasing factor agonist: effect on growth, sexual maturation, pelvic sonography, and the hypothalamic-pituitary-gonadal axis. Styne, D.M., Harris, D.A., Egli, C.A., Conte, F.A., Kaplan, S.L., Rivier, J., Vale, W., Grumbach, M.M. J. Clin. Endocrinol. Metab. (1985) [Pubmed]
  21. TTF-1, a homeodomain gene required for diencephalic morphogenesis, is postnatally expressed in the neuroendocrine brain in a developmentally regulated and cell-specific fashion. Lee, B.J., Cho, G.J., Norgren, R.B., Junier, M.P., Hill, D.F., Tapia, V., Costa, M.E., Ojeda, S.R. Mol. Cell. Neurosci. (2001) [Pubmed]
  22. Expression of the neurotransmitter-synthesizing enzyme glutamic acid decarboxylase in male germ cells. Persson, H., Pelto-Huikko, M., Metsis, M., Söder, O., Brene, S., Skog, S., Hökfelt, T., Ritzén, E.M. Mol. Cell. Biol. (1990) [Pubmed]
  23. Testosterone mediates expression of the selenoprotein PHGPx by induction of spermatogenesis and not by direct transcriptional gene activation. Maiorino, M., Wissing, J.B., Brigelius-Flohé, R., Calabrese, F., Roveri, A., Steinert, P., Ursini, F., Flohé, L. FASEB J. (1998) [Pubmed]
  24. Sexual maturation-associated and estrogen-induced progesterone receptor expression in the bursa of Fabricius. Ylikomi, T.J., Isola, J.J., Gasc, J.M., Tuohimaa, P.J. J. Immunol. (1987) [Pubmed]
  25. Determinants of plasma retinol, beta-carotene, and alpha-tocopherol during adolescence. Herbeth, B., Spyckerelle, Y., Deschamps, J.P. Am. J. Clin. Nutr. (1991) [Pubmed]
  26. Changes in distribution and androgen production of Leydig cells of two populations during sexual maturation in the rat. Chase, D.J., Payne, A.H. Endocrinology (1983) [Pubmed]
  27. Effects of diet and sexual maturation on low-density lipoprotein cholesterol during puberty: the Dietary Intervention Study in Children (DISC). Kwiterovich, P.O., Barton, B.A., McMahon, R.P., Obarzanek, E., Hunsberger, S., Simons-Morton, D., Kimm, S.Y., Friedman, L.A., Lasser, N., Robson, A., Lauer, R., Stevens, V., Van Horn, L., Gidding, S., Snetselaar, L., Hartmuller, V.W., Greenlick, M., Franklin, F. Circulation (1997) [Pubmed]
  28. Hormonal control of plasma renin substrate; (angiotensinogen). Krakoff, L.R., Eisenfeld, A.J. Circ. Res. (1977) [Pubmed]
  29. Tissue-specific developmental expression of the kallikrein gene family in the rat. Clements, J.A., Matheson, B.A., Funder, J.W. J. Biol. Chem. (1990) [Pubmed]
  30. Growth and sexual maturation during long-term treatment with risperidone. Dunbar, F., Kusumakar, V., Daneman, D., Schulz, M. The American journal of psychiatry. (2004) [Pubmed]
  31. Adrenal steroid, cortisol, adrenocorticotropin, and beta-endorphin responses to human corticotropin-releasing hormone stimulation test in normal children and children with premature pubarche. Ghizzoni, L., Virdis, R., Ziveri, M., Lamborghini, A., Alberini, A., Volta, C., Bernasconi, S. J. Clin. Endocrinol. Metab. (1989) [Pubmed]
  32. Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2. Matsumoto, S., Yamazaki, C., Masumoto, K.H., Nagano, M., Naito, M., Soga, T., Hiyama, H., Matsumoto, M., Takasaki, J., Kamohara, M., Matsuo, A., Ishii, H., Kobori, M., Katoh, M., Matsushime, H., Furuichi, K., Shigeyoshi, Y. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  33. Developmental regulation of gonadotropin-releasing hormone gene expression by the MSX and DLX homeodomain protein families. Givens, M.L., Rave-Harel, N., Goonewardena, V.D., Kurotani, R., Berdy, S.E., Swan, C.H., Rubenstein, J.L., Robert, B., Mellon, P.L. J. Biol. Chem. (2005) [Pubmed]
  34. Differential expression of secretogranin II and chromogranin A genes in the female rat pituitary through sexual maturation and estrous cycle. Anouar, Y., Duval, J. Endocrinology (1991) [Pubmed]
  35. Serum prolactin and luteinizing hormone levels and the activities of hypothalamic monoamine oxidase A and B and phenylethanolamine-N-methyl transferase are changed during sexual maturation in male rats treated neonatally with melatonin. Moreno, M.L., Villanúa, M.A., Esquifino, A.I. J. Pineal Res. (1992) [Pubmed]
  36. Leptin is a metabolic gate for the onset of puberty in the female rat. Cheung, C.C., Thornton, J.E., Kuijper, J.L., Weigle, D.S., Clifton, D.K., Steiner, R.A. Endocrinology (1997) [Pubmed]
  37. Growth hormone (GH) deprivation induced by passive immunization against rat GH-releasing factor does not disturb the course of sexual maturation and fertility in the female rat. Gruaz, N.M., Arsenijevic, Y., Wehrenberg, W.B., Sizonenko, P.C., Aubert, M.L. Endocrinology (1994) [Pubmed]
  38. Differential expression and regulation of prostaglandin E synthases in the mouse ovary during sexual maturation and luteal development. Sun, T., Deng, W.B., Diao, H.L., Ni, H., Bai, Y.Y., Ma, X.H., Xu, L.B., Yang, Z.M. J. Endocrinol. (2006) [Pubmed]
  39. Identification and expression of epidermal growth factor gene in mouse testis. Zhang, M.L., Yan, Y.C., Sun, Y.P., Koide, S.S. Cell Res. (1997) [Pubmed]
  40. Reproductive effects in male and female rats of neonatal exposure to genistein. Nagao, T., Yoshimura, S., Saito, Y., Nakagomi, M., Usumi, K., Ono, H. Reprod. Toxicol. (2001) [Pubmed]
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