Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

Clcn7 - chloride channel, voltage-sensitive 7

Rattus norvegicus

Synonyms: Chloride channel 7 alpha subunit, Chloride channel protein 7, ClC-7, H(+)/Cl(-) exchange transporter 7

Kulka, M. et al., Diewald, L. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Clcn7

We therefore suggest that ClC-7 in oocytes is a functional chloride current at acidic pH [1].
Using Western Blotting, we found protein expression of ClC-2 and ClC-7, but not ClC-3, in RCMC, whereas in PMC neither of these proteins could be detected [2].

Analytical, diagnostic and therapeutic context of Clcn7

RESULTS: RT-PCR showed that RCMC expressed mRNA for the Cl- channels (ClC)-2, -3, -4, -5 and -7, while PMC expressed ClC-7 [2].

References

Activation by acidic pH of CLC-7 expressed in oocytes from Xenopus laevis. Diewald, L., Rupp, J., Dreger, M., Hucho, F., Gillen, C., Nawrath, H. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
Mast cells express chloride channels of the ClC family. Kulka, M., Schwingshackl, A., Befus, A.D. Inflamm. Res. (2002) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP007499	Anopheles gambiae str. PEST
CLC-C	Arabidopsis thaliana
AT5G33280	Arabidopsis thaliana
CLCN7	Bos taurus
clh-6	Caenorhabditis elegans
CLCN7	Canis lupus familiaris
clcn7	Danio rerio
ClC-b	Drosophila melanogaster
CLCN7	Gallus gallus
CLCN7	Homo sapiens
CLCN7	Macaca mulatta
Clcn7	Mus musculus
CLCN7	Pan troglodytes
clcn7	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.