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Gene Review

Clcn7  -  chloride channel, voltage-sensitive 7

Rattus norvegicus

Synonyms: Chloride channel 7 alpha subunit, Chloride channel protein 7, ClC-7, H(+)/Cl(-) exchange transporter 7
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High impact information on Clcn7


Analytical, diagnostic and therapeutic context of Clcn7

  • RESULTS: RT-PCR showed that RCMC expressed mRNA for the Cl- channels (ClC)-2, -3, -4, -5 and -7, while PMC expressed ClC-7 [2].


  1. Activation by acidic pH of CLC-7 expressed in oocytes from Xenopus laevis. Diewald, L., Rupp, J., Dreger, M., Hucho, F., Gillen, C., Nawrath, H. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  2. Mast cells express chloride channels of the ClC family. Kulka, M., Schwingshackl, A., Befus, A.D. Inflamm. Res. (2002) [Pubmed]
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