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Gene Review

Clcn7  -  chloride channel 7

Mus musculus

Synonyms: AA409691, AW538136, Chloride channel 7 alpha subunit, Chloride channel protein 7, ClC-7, ...
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Disease relevance of Clcn7


High impact information on Clcn7


Anatomical context of Clcn7


Analytical, diagnostic and therapeutic context of Clcn7


  1. ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function. Lange, P.F., Wartosch, L., Jentsch, T.J., Fuhrmann, J.C. Nature (2006) [Pubmed]
  2. The expression of clcn7 and ostm1 in osteoclasts is coregulated by microphthalmia transcription factor. Meadows, N.A., Sharma, S.M., Faulkner, G.J., Ostrowski, M.C., Hume, D.A., Cassady, A.I. J. Biol. Chem. (2007) [Pubmed]
  3. Expression of mouse osteoclast K-Cl Co-transporter-1 and its role during bone resorption. Kajiya, H., Okamoto, F., Li, J.P., Nakao, A., Okabe, K. J. Bone Miner. Res. (2006) [Pubmed]
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