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Gene Review:

Gstt2 - glutathione S-transferase, theta 2

Rattus norvegicus

Synonyms: GST 12-12, GST class-theta-2, Glutathione S-transferase 12, Glutathione S-transferase Yrs-Yrs, Glutathione S-transferase theta-2

Jemth, P. et al., Ogura, K. et al., Hiratsuka, A. et al.

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Disease relevance of Gstt2

Rat glutathione transferase (GST) T2-2 of class Theta (rGST T2-2), previously known as GST 12-12 and GST Yrs-Yrs, has been heterologously expressed in Escherichia coli XLI-Blue [1].

High impact information on Gstt2

A new class of rat glutathione S-transferase Yrs-Yrs inactivating reactive sulfate esters as metabolites of carcinogenic arylmethanols [2].

Analytical, diagnostic and therapeutic context of Gstt2

Molecular cloning and amino acid sequencing of rat liver class theta glutathione S-transferase Yrs-Yrs inactivating reactive sulfate esters of carcinogenic arylmethanols [3].

References

Heterologous expression, purification and characterization of rat class theta glutathione transferase T2-2. Jemth, P., Stenberg, G., Chaga, G., Mannervik, B. Biochem. J. (1996) [Pubmed]
A new class of rat glutathione S-transferase Yrs-Yrs inactivating reactive sulfate esters as metabolites of carcinogenic arylmethanols. Hiratsuka, A., Sebata, N., Kawashima, K., Okuda, H., Ogura, K., Watabe, T., Satoh, K., Hatayama, I., Tsuchida, S., Ishikawa, T. J. Biol. Chem. (1990) [Pubmed]
Molecular cloning and amino acid sequencing of rat liver class theta glutathione S-transferase Yrs-Yrs inactivating reactive sulfate esters of carcinogenic arylmethanols. Ogura, K., Nishiyama, T., Okada, T., Kajital, J., Narihata, H., Watabe, T., Hiratsuka, A., Watabe, T. Biochem. Biophys. Res. Commun. (1991) [Pubmed]

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LOC100686488	Canis lupus familiaris
GSTT2	Homo sapiens
GSTT2B	Homo sapiens
GSTT2	Macaca mulatta
Gstt2	Mus musculus
LOC458962	Pan troglodytes

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