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Gene Review

GSTT2  -  glutathione S-transferase theta 2...

Homo sapiens

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Disease relevance of GSTT2


High impact information on GSTT2


Biological context of GSTT2


Associations of GSTT2 with chemical compounds


Analytical, diagnostic and therapeutic context of GSTT2


  1. GSTT2 promoter polymorphisms and colorectal cancer risk. Jang, S.G., Kim, I.J., Kang, H.C., Park, H.W., Ahn, S.A., Yoon, H.J., Kim, K., Shin, H.R., Lee, J.S., Park, J.G. BMC Cancer (2007) [Pubmed]
  2. Butyrate may enhance toxicological defence in primary, adenoma and tumor human colon cells by favourably modulating expression of glutathione S-transferases genes, an approach in nutrigenomics. Pool-Zobel, B.L., Selvaraju, V., Sauer, J., Kautenburger, T., Kiefer, J., Richter, K.K., Soom, M., Wölfl, S. Carcinogenesis (2005) [Pubmed]
  3. Structure and organization of the human theta-class glutathione S-transferase and D-dopachrome tautomerase gene complex. Coggan, M., Whitbread, L., Whittington, A., Board, P. Biochem. J. (1998) [Pubmed]
  4. Apple flavonoids inhibit growth of HT29 human colon cancer cells and modulate expression of genes involved in the biotransformation of xenobiotics. Veeriah, S., Kautenburger, T., Habermann, N., Sauer, J., Dietrich, H., Will, F., Pool-Zobel, B.L. Mol. Carcinog. (2006) [Pubmed]
  5. Molecular cloning of a cDNA and chromosomal localization of a human theta-class glutathione S-transferase gene (GSTT2) to chromosome 22. Tan, K.L., Webb, G.C., Baker, R.T., Board, P.G. Genomics (1995) [Pubmed]
  6. Characterization of a cDNA and gene encoding the mouse theta class glutathione transferase mGSTT2 and its localization to chromosome 10B5-C1. Whittington, A.T., Webb, G.C., Baker, R.T., Board, P.G. Genomics (1996) [Pubmed]
  7. Genetic heterogeneity of the structure and function of GSTT2 and GSTP1. Board, P., Harris, M., Flanagan, J., Langton, L., Coggan, M. Chem. Biol. Interact. (1998) [Pubmed]
  8. Homology model for the human GSTT2 Theta class glutathione transferase. Chelvanayagam, G., Wilce, M.C., Parker, M.W., Tan, K.L., Board, P.G. Proteins (1997) [Pubmed]
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