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HIST1H1D  -  histone cluster 1, H1d

Homo sapiens

Synonyms: H1.3, H1D, H1F3, H1d, H1s-2, ...
 
 
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High impact information on HIST1H1D

  • The H1.4 gene is associated with an H2B gene, whereas genes coding for all four core histones are located in the vicinity of the H1.3 gene [1].
  • Two human H1 histone genes, termed H1.3 and H1.4, were isolated from two cosmid clones [1].
  • Mutation analysis indicates that the CH1UE motif is involved in mediating the S-phase-dependent expression of the H1.3 gene [2].
  • Analysis of the H1.3 gene promoter was carried out with reporter gene assays (using the luciferase gene as a reporter gene) including stepwise deletion and site-directed mutagenesis [2].

References

  1. Isolation and characterization of two human H1 histone genes within clusters of core histone genes. Albig, W., Kardalinou, E., Drabent, B., Zimmer, A., Doenecke, D. Genomics (1991) [Pubmed]
  2. Conserved sequence elements in human main type-H1 histone gene promoters: their role in H1 gene expression. Meergans, T., Albig, W., Doenecke, D. Eur. J. Biochem. (1998) [Pubmed]
 
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