Gene Review:
srfa - serum response factor a
Danio rerio
Synonyms:
SO:0000704, srf, srf1
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High impact information on srf
- We have characterized srf expression during early zebrafish embryogenesis [1].
- In addition to low-level expression in many or even all cells, elevated levels of srf RNA and protein are transiently expressed in skeletal muscle lineages during their differentiation [1].
- Serum response factor (SRF) was identified as an activity binding upon serum stimulation of HeLa cells to a motif known as the serum response element in the c-fos promoter [1].
References
- A zebrafish homolog of the serum response factor gene is highly expressed in differentiating embryonic myocytes. Vogel, A.M., Gerster, T. Mech. Dev. (1999) [Pubmed]
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