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Gene Review

igf2a  -  insulin-like growth factor 2a

Danio rerio

Synonyms: IGF-II, SO:0000704, igf2, igf2b, wu:fc26e03, ...
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High impact information on igf2

  • Sequence comparison showed that the primary structures of zebrafish IGF-I, IGF-II, and IGF-I receptors (IGF-IRs) have been highly conserved in vertebrates [1].
  • Elevated levels of expression of IGFBP-3 were observed 24 hours after injection with IGF-I and 48 hours with IGF-II or insulin [2].


  1. Structural, biochemical, and expression analysis of two distinct insulin-like growth factor I receptors and their ligands in zebrafish. Maures, T., Chan, S.J., Xu, B., Sun, H., Ding, J., Duan, C. Endocrinology (2002) [Pubmed]
  2. Molecular cloning and tissue-specific, developmental-stage-specific, and hormonal regulation of IGFBP3 gene in zebrafish. Chen, J.Y., Chen, J.C., Huang, W.T., Liu, C.W., Hui, C.F., Chen, T.T., Wu, J.L. Mar. Biotechnol. (2004) [Pubmed]
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