High impact information on Kap3

• All these defects are rescued by exclusive expression of DmKAP and KLP64D/KIF3A in the JO neurons of respective mutants [1].
• Follicle separation during Drosophila oogenesis requires the activity of the kinesin II-associated polypeptide Kap in germline cells [2].
• We have generated Kap mutants and show that gene activity is not only required for neuronal function but also for separation of follicles during early oogenesis [2].
• Kap was shown to transport both particulate cargo, as axoneme components in rafts, and membrane-bounded organelles such as melanosomes [2].

Other interactions of Kap3

• The DmKAP expression pattern in the nervous system corresponds well with that of Klp64D and Klp68D as reported earlier [3].

Analytical, diagnostic and therapeutic context of Kap3

• In situ hybridization using a DmKAP specific cRNA probe has revealed a dynamic pattern of expression in the developing nervous system [3].

References