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Gene Review

RhoGAPp190  -  Rho GTPase activating protein p190

Drosophila melanogaster

Synonyms: 8267, BcDNA:GH17919, BcDNA:GM05133, CG32555, CG8240, ...
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High impact information on RhoGAPp190

  • Central spindle assembly is mediated by a microtubule-associated protein and a kinesin-RhoGAP complex, both of which are regulated by phosphorylation/dephosphorylation [1].
  • The RhoGAP crossveinless-c links trachealess and EGFR signaling to cell shape remodeling in Drosophila tracheal invagination [2].
  • The corresponding cDNA encodes a predicted 30 kDa subunit containing a Ras homologous GTPase Activating Protein (RhoGAP) domain, suggesting a possible involvement in the regulation of actin cytoskeleton changes [3].
  • The implication of the P4 protein in suppressing the host cellular immunity is discussed in correlation with its predicted molecular function as a Rho-GAP protein [4].


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