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Gene Review

dnaK  -  molecular chaperone DnaK

Chlamydophila abortus S26/3

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Disease relevance of dnaK

  • In order to enhance the quantity and the protective properties of the antibodies induced by DNA vaccination with the heat shock protein dnaK gene of Chlamydophila abortus AB7 as well as to elicit an efficient cellular immune response, we vaccinated mice with a DNA prime followed by a boost with the recombinant DnaK protein [1].
  • No delayed-type hypersensitivity reaction was observed and the spleens of dnaK vaccinated-mice were not protected against C. abortus challenge [2].

High impact information on dnaK


Biological context of dnaK

  • Mice were intramuscularly immunized with a dnaK-encoding DNA plasmid [2].


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