Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

eIF-4B - Eukaryotic initiation factor 4B

Drosophila melanogaster

Synonyms: CG10837, Dm-eIF4B, Dmel\CG10837, EIF-4B, Eif4B, ...

Hernández, G. et al.

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High impact information on eIF-4B

RNA interference experiments suggest that eIF4B is required for cell survival, although only a modest reduction in rate of protein synthesis is observed [1].
Both eIF4B mRNAs and proteins are expressed during the entire embryogenesis and life cycle [1].
Overexpression of eIF4B in Drosophila cells in culture and in developing eye imaginal discs promotes cell proliferation [1].

References

Two functionally redundant isoforms of Drosophila melanogaster eukaryotic initiation factor 4B are involved in cap-dependent translation, cell survival, and proliferation. Hernández, G., Vázquez-Pianzola, P., Zurbriggen, A., Altmann, M., Sierra, J.M., Rivera-Pomar, R. Eur. J. Biochem. (2004) [Pubmed]

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