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Gene Review

myoC  -  class I myosin

Dictyostelium discoideum AX4

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High impact information on myoC


Biological context of myoC

  • Various properties of the endosomal pathway in the myoB-/C- double mutant as well as in the myoB- and myoC- single mutants, including intravesicular pH, and intracellular retention time and exocytosis of a fluid phase marker, were found to be indistinguishable from wild-type parental cells [1].


  1. Examination of the endosomal and lysosomal pathways in Dictyostelium discoideum myosin I mutants. Temesvari, L.A., Bush, J.M., Peterson, M.D., Novak, K.D., Titus, M.A., Cardelli, J.A. J. Cell. Sci. (1996) [Pubmed]
  2. The Dictyostelium class I myosin, MyoD, contains a novel light chain that lacks high-affinity calcium-binding sites. De La Roche, M.A., Lee, S.F., Côté, G.P. Biochem. J. (2003) [Pubmed]
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