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Gene Review

dream  -  CG7863 gene product from transcript CG7863-RB

Drosophila melanogaster

Synonyms: CG7863, DREAM, Dmel\CG7863, Dream, Dream/Strica, ...
 
 
 
 
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High impact information on dream

  • STRICA is a caspase with a long amino-terminal prodomain that lacks any caspase recruitment domain or death effector domain [1].
  • Interestingly, unlike other fly caspases, STRICA showed physical association with DIAP2, in cotransfection experiments [1].
  • STRICA is a cytoplasmic protein that, upon overexpression, caused apoptosis in cultured Drosophila SL2 cells that was partially suppressed by DIAP1 [1].
  • Instead, the prodomain of STRICA consists of unique serine/threonine stretches [1].
  • Low levels of strica expression were detected in embryos, larvae, pupae and adult animals [1].
 

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References

 
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