Gene Review:
fra - frazzled
Drosophila melanogaster
Synonyms:
CG8581, CT24981, DCC, Dmel\CG8581, Fra
- frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance. Kolodziej, P.A., Timpe, L.C., Mitchell, K.J., Fried, S.R., Goodman, C.S., Jan, L.Y., Jan, Y.N. Cell (1996)
- The Abelson tyrosine kinase, the Trio GEF and Enabled interact with the Netrin receptor Frazzled in Drosophila. Forsthoefel, D.J., Liebl, E.C., Kolodziej, P.A., Seeger, M.A. Development (2005)
- The netrin receptor frazzled is required in the target for establishment of retinal projections in the Drosophila visual system. Gong, Q., Rangarajan, R., Seeger, M., Gaul, U. Development (1999)
- Altered levels of Gq activity modulate axonal pathfinding in Drosophila. Ratnaparkhi, A., Banerjee, S., Hasan, G. J. Neurosci. (2002)
- Engrailed controls the organization of the ventral nerve cord through frazzled regulation. Joly, W., Mugat, B., Maschat, F. Dev. Biol. (2007)