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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

pilR  -  integral membrane protein

Escherichia coli

 
 
 
 
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High impact information on pilR

  • PilR was overproduced by fusing pilR to the gene for the maltose-binding protein (malE), yielding a MalE-PilR hybrid protein [1].
  • The plasmid with the malE-pilR fusion, when introduced into a non-piliated pilR mutant strain of P. aeruginosa, restored piliation, indicating that the hybrid protein retains PilR function in vivo [1].
  • Integral membrane proteins required for bacterial motility and chemotaxis [2].

References

  1. PilR, a transcriptional regulator of piliation in Pseudomonas aeruginosa, binds to a cis-acting sequence upstream of the pilin gene promoter. Jin, S., Ishimoto, K.S., Lory, S. Mol. Microbiol. (1994) [Pubmed]
  2. Integral membrane proteins required for bacterial motility and chemotaxis. Boyd, A., Mandel, G., Simon, M.I. Symp. Soc. Exp. Biol. (1982) [Pubmed]
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