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Gene Review

Dh44-R1  -  Diuretic hormone 44 receptor 1

Drosophila melanogaster

Synonyms: CG8422, DH-R, DH44-R1, DH[[44]]-R1, DmeCG8422, ...
 
 
 
 
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High impact information on CG8422

  • The Drosophila genome contains two genes (CG8422 and CG12370) orthologous to Manduca and Acheta DH-Rs [1].
  • By microarray analysis, the CG8422 transcript was detectable in Drosophila head mRNA of different genotypes and under different environmental conditions [1].
  • When expressed in mammalian cells, CG8422 conferred selective sensitivity to DH, as indicated by translocation of a beta-arrestin-2-GFP reporter from the cytoplasm to the cell membrane [1].

References

  1. Drosophila CG8422 encodes a functional diuretic hormone receptor. Johnson, E.C., Bohn, L.M., Taghert, P.H. J. Exp. Biol. (2004) [Pubmed]
 
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