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Gene Review

ITGB6  -  integrin, beta 6

Homo sapiens

Synonyms: Integrin beta-6
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Disease relevance of ITGB6

  • Furthermore, Itgb6-/- mice are also protected from ventilator-induced lung edema [1].

High impact information on ITGB6


  1. Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. Jenkins, R.G., Su, X., Su, G., Scotton, C.J., Camerer, E., Laurent, G.J., Davis, G.E., Chambers, R.C., Matthay, M.A., Sheppard, D. J. Clin. Invest. (2006) [Pubmed]
  2. Regional localization of the human integrin beta 6 gene (ITGB6) to chromosome 2q24-q31. Fernández-Ruiz, E., Sánchez-Madrid, F. Genomics (1994) [Pubmed]
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