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Gene Review:

crtB - phytoene synthase

Rhodobacter sphaeroides 2.4.1

Lang, H.P. et al.

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Disease relevance of crtB

Early steps in carotenoid biosynthesis: sequences and transcriptional analysis of the crtI and crtB genes of Rhodobacter sphaeroides and overexpression and reactivation of crtI in Escherichia coli and R. sphaeroides [1].

High impact information on crtB

In this report, we have located the transcription initiation point and have shown that R. sphaeroides possesses an oxygen-regulated CrtI-type phytoene desaturase gene that forms a transcriptional operon with crtB [1].

Biological context of crtB

In this report, we present the DNA and deduced amino acid sequences of the genes encoding these proteins, namely, crtB and crtI, from R. sphaeroides and present evidence for the existence of a crtIB operon [1].

Other interactions of crtB

Although the crtI and crtB genes have been sequenced from a number of different organisms, the transcriptional organization and regulation of these genes have not been analyzed in detail [1].

References

Early steps in carotenoid biosynthesis: sequences and transcriptional analysis of the crtI and crtB genes of Rhodobacter sphaeroides and overexpression and reactivation of crtI in Escherichia coli and R. sphaeroides. Lang, H.P., Cogdell, R.J., Gardiner, A.T., Hunter, C.N. J. Bacteriol. (1994) [Pubmed]

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