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Gene Review:

FZD10 - frizzled family receptor 10

Gallus gallus

Kawakami, Y. et al., Kawakami, Y. et al.

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High impact information on FZD10

Implantation of Sonic hedgehog (Shh)-expressing cells into the anterior margin of the limb bud resulted in the induction of Fz-10 expression in anterior-dorsal mesenchyme [1].
Identification of chick frizzled-10 expressed in the developing limb and the central nervous system [1].
Fz-10 is also expressed in the feather bud and branchial arch [1].
Fz-10 is expressed in the region posterior to the Hensen's node at stage 6 [1].
Fz-10 transcripts colocalize with Sonic hedgehog (Shh) in the dorsal side of stages 18-23 chick limb buds [2].

Anatomical context of FZD10

In the developing limb, Fz-10 expression starts at stage 18 in the posterior-dorsal region of the distal mesenchyme, and gradually expands to the anterior-distal region [1].

References

Identification of chick frizzled-10 expressed in the developing limb and the central nervous system. Kawakami, Y., Wada, N., Nishimatsu, S., Komaguchi, C., Noji, S., Nohno, T. Mech. Dev. (2000) [Pubmed]
Involvement of frizzled-10 in Wnt-7a signaling during chick limb development. Kawakami, Y., Wada, N., Nishimatsu, S., Nohno, T. Dev. Growth Differ. (2000) [Pubmed]

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