Gene Review:
SAT1 - spermidine/spermine N1-acetyltransferase 1
Gallus gallus
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High impact information on SAT1
- One of the selected genes, spermidine/spermine N(1)-acetyltransferase (SSAT), was preferentially expressed in the dorsal-temporal quadrant of the developing retina [1].
- The elevated levels of SSAT mRNA in Müller glial cells may reflect a requirement for acetylated spermine/spermidine or putrescine in the differentiating neuronal cells of the retina [1].
Anatomical context of SAT1
- SSAT mRNA was found in Müller glial cells and its distribution pattern in these cells closely followed the three differentiation axes of the developing retina, with a central-dorsal-temporal preference [1].
References
- Expression of spermidine/spermine N(1)-acetyltransferase in the Müller glial cells of the developing chick retina. Witte, R.L., Godbout, R. Exp. Eye Res. (2002) [Pubmed]
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