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Gene Review

SAT1  -  spermidine/spermine N1-acetyltransferase 1

Gallus gallus

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High impact information on SAT1

  • One of the selected genes, spermidine/spermine N(1)-acetyltransferase (SSAT), was preferentially expressed in the dorsal-temporal quadrant of the developing retina [1].
  • The elevated levels of SSAT mRNA in Müller glial cells may reflect a requirement for acetylated spermine/spermidine or putrescine in the differentiating neuronal cells of the retina [1].

Anatomical context of SAT1

  • SSAT mRNA was found in Müller glial cells and its distribution pattern in these cells closely followed the three differentiation axes of the developing retina, with a central-dorsal-temporal preference [1].


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