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Gene Review:

KIF7 - kinesin family member 7

Homo sapiens

Synonyms: ACLS, HLS2, JBTS12, Kinesin-like protein KIF7, UNQ340, ...

Katoh, Y. et al., Katoh, Y. et al., Katoh, M. et al., Katoh, Y. et al.

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Disease relevance of KIF7

KIF7 mRNA was expressed in embryonic stem (ES) cells, melanotic melanoma and Jurkat T cells, while KIF27 mRNA was expressed in testis, pancreatic islet, germ cell tumors and Jurkat T cells [1].

High impact information on KIF7

KIF27 gene at human chromosome 9q22.1 and KIF7 gene at human chromosome 15q26.1 were paralogs within the human genome [2].
Here we characterized human KIF7 gene by using bioinformatics [1].
KIF7 gene, consisting of 19 exons, was found to encode a 1343-amino-acid KIF7 protein [1].
NM_138424.1 RefSeq encoded a 513-amino-acid aberrant KIF7 protein with N-terminal-truncation, while KIF12 complete CDS encoded a 651-amino-acid full-length KIF12 protein [3].

Other interactions of KIF7

Iguana homologs (DZIP1 and DZIP1L) and Costal-2 homologs (KIF7 and KIF27) are identified by comparative integromics [4].

References

Characterization of KIF7 gene in silico. Katoh, Y., Katoh, M. Int. J. Oncol. (2004) [Pubmed]
KIF27 is one of orthologs for Drosophila Costal-2. Katoh, Y., Katoh, M. Int. J. Oncol. (2004) [Pubmed]
Characterization of KIF12 gene in silico. Katoh, M., Katoh, M. Oncol. Rep. (2005) [Pubmed]
Hedgehog signaling pathway and gastrointestinal stem cell signaling network (Review). Katoh, Y., Katoh, M. Int. J. Mol. Med. (2006) [Pubmed]

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KIF7	Bos taurus
KIF7	Canis lupus familiaris
kif7	Danio rerio
KIF7	Gallus gallus
KIF7	Macaca mulatta
Kif7	Mus musculus
KIF7	Pan troglodytes
Kif7	Rattus norvegicus

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