MeSH Review:
Islets of Langerhans
Wong,
Visintin,
Wen,
Granata,
Flavell,
Janeway,
Grohmann,
Orabona,
Fallarino,
Vacca,
Calcinaro,
Falorni,
Candeloro,
Belladonna,
Bianchi,
Fioretti,
Puccetti,
Robertson,
Tanaka,
Takahashi,
Tran,
Harmon,
Waeber,
Delplanque,
Bonny,
Mooser,
Steinmann,
Widmann,
Maillard,
Miklossy,
Dina,
Hani,
Vionnet,
Nicod,
Boutin,
Froguel,
Pugliese,
Zeller,
Fernandez,
Zalcberg,
Bartlett,
Ricordi,
Pietropaolo,
Eisenbarth,
Bennett,
Patel,
Kulkarni,
Holzenberger,
Shih,
Ozcan,
Stoffel,
Magnuson,
Kahn,
Kim,
Selleri,
Lee,
Zhang,
Gu,
Jacobs,
Cleary,
- Inhibition of glucose transport into rat islet cells by immunoglobulins from patients with new-onset insulin-dependent diabetes mellitus. Johnson, J.H., Crider, B.P., McCorkle, K., Alford, M., Unger, R.H. N. Engl. J. Med. (1990)
- The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. Pugliese, A., Zeller, M., Fernandez, A., Zalcberg, L.J., Bartlett, R.J., Ricordi, C., Pietropaolo, M., Eisenbarth, G.S., Bennett, S.T., Patel, D.D. Nat. Genet. (1997)
- "Somatostatinoma": a somatostatin-containing tumor of the endocrine pancreas. Ganda, O.P., Weir, G.C., Soeldner, J.S., Legg, M.A., Chick, W.L., Patel, Y.C., Ebeid, A.M., Gabbay, K.H., Reichlin, S. N. Engl. J. Med. (1977)
- Pancreatic cholera: benefical effects of treatment with streptozotocin. Kahn, C.R., Levy, A.G., Gardner, J.D., Miller, J.V., Gorden, P., Schein, P.S. N. Engl. J. Med. (1975)
- Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus. Lorenzo, A., Razzaboni, B., Weir, G.C., Yankner, B.A. Nature (1994)
- Prevention of oxidative stress by adenoviral overexpression of glutathione-related enzymes in pancreatic islets. Robertson, R.P., Tanaka, Y., Takahashi, H., Tran, P.O., Harmon, J.S. Ann. N. Y. Acad. Sci. (2005)
- Anomeric specificity of hexose metabolism in pancreatic islets. Malaisse, W.J., Malaisse-Lagae, F., Sener, A. Physiol. Rev. (1983)
- Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes. Meyre, D., Bouatia-Naji, N., Tounian, A., Samson, C., Lecoeur, C., Vatin, V., Ghoussaini, M., Wachter, C., Hercberg, S., Charpentier, G., Patsch, W., Pattou, F., Charles, M.A., Tounian, P., Clément, K., Jouret, B., Weill, J., Maddux, B.A., Goldfine, I.D., Walley, A., Boutin, P., Dina, C., Froguel, P. Nat. Genet. (2005)
- The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector. Screaton, R.A., Conkright, M.D., Katoh, Y., Best, J.L., Canettieri, G., Jeffries, S., Guzman, E., Niessen, S., Yates, J.R., Takemori, H., Okamoto, M., Montminy, M. Cell (2004)
- beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass. Kulkarni, R.N., Holzenberger, M., Shih, D.Q., Ozcan, U., Stoffel, M., Magnuson, M.A., Kahn, C.R. Nat. Genet. (2002)
- Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus. Kim, S.K., Selleri, L., Lee, J.S., Zhang, A.Y., Gu, X., Jacobs, Y., Cleary, M.L. Nat. Genet. (2002)
- Trifluoperazine reversal of secretory diarrhea in pancreatic cholera. Donowitz, M., Elta, G., Bloom, S.R., Nathanson, L. Ann. Intern. Med. (1980)
- Tumorigenic action of streptozotocin on the pancreas and kidney in male Wistar rats. Kazumi, T., Yoshino, G., Fujii, S., Baba, S. Cancer Res. (1978)
- Phase II trial of chlorozotocin and fluorouracil in islet cell carcinoma: a Southwest Oncology Group study. Bukowski, R.M., Tangen, C., Lee, R., Macdonald, J.S., Einstein, A.B., Peterson, R., Fleming, T.R. J. Clin. Oncol. (1992)
- Antigens associated with human squamous cell lung carcinoma defined by murine monoclonal antibodies. Fernsten, P.D., Pekny, K.W., Reisfeld, R.A., Walker, L.E. Cancer Res. (1986)
- High concentration of gamma-aminobutyric acid in pancreatic beta cells. Taniguchi, H., Okada, Y., Seguchi, H., Shimada, C., Seki, M., Tsutou, A., Baba, S. Diabetes (1979)
- Factors associated with early remission of type I diabetes in children treated with cyclosporine. Bougneres, P.F., Carel, J.C., Castano, L., Boitard, C., Gardin, J.P., Landais, P., Hors, J., Mihatsch, M.J., Paillard, M., Chaussain, J.L. N. Engl. J. Med. (1988)
- Proliferation, senescence, and neoplastic progression of beta cells in hyperplasic pancreatic islets. Teitelman, G., Alpert, S., Hanahan, D. Cell (1988)
- Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Garcia Soriano F, n.u.l.l., Virág, L., Jagtap, P., Szabó, E., Mabley, J.G., Liaudet, L., Marton, A., Hoyt, D.G., Murthy, K.G., Salzman, A.L., Southan, G.J., Szabó, C. Nat. Med. (2001)
- Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells. Ahlgren, U., Pfaff, S.L., Jessell, T.M., Edlund, T., Edlund, H. Nature (1997)
- The role of lymphocyte subsets in accelerated diabetes in nonobese diabetic-rat insulin promoter-B7-1 (NOD-RIP-B7-1) mice. Wong, F.S., Visintin, I., Wen, L., Granata, J., Flavell, R., Janeway, C.A. J. Exp. Med. (1998)
- Identification of human glandular kallikrein in the beta cell of the pancreas. ole-MoiYoi, O.K., Pinkus, G.S., Spragg, J., Austen, K.F. N. Engl. J. Med. (1979)
- Direct evidence for the contribution of the unique I-ANOD to the development of insulitis in non-obese diabetic mice. Miyazaki, T., Uno, M., Uehira, M., Kikutani, H., Kishimoto, T., Kimoto, M., Nishimoto, H., Miyazaki, J., Yamamura, K. Nature (1990)
- Ca2+-activated ATPase and ATP-dependent calmodulin-stimulated Ca2+ transport in islet cell plasma membrane. Pershadsingh, H.A., McDaniel, M.L., Landt, M., Bry, C.G., Lacy, P.E., McDonald, J.M. Nature (1980)
- Translational control of proinsulin synthesis by glucose. Itoh, N., Okamoto, H. Nature (1980)
- Streptozocin-doxorubicin, streptozocin-fluorouracil or chlorozotocin in the treatment of advanced islet-cell carcinoma. Moertel, C.G., Lefkopoulo, M., Lipsitz, S., Hahn, R.G., Klaassen, D. N. Engl. J. Med. (1992)
- Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets. Yamamoto, H., Uchigata, Y., Okamoto, H. Nature (1981)
- Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus. Malecki, M.T., Jhala, U.S., Antonellis, A., Fields, L., Doria, A., Orban, T., Saad, M., Warram, J.H., Montminy, M., Krolewski, A.S. Nat. Genet. (1999)
- Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice. Harrison, K.A., Thaler, J., Pfaff, S.L., Gu, H., Kehrl, J.H. Nat. Genet. (1999)
- The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes. Waeber, G., Delplanque, J., Bonny, C., Mooser, V., Steinmann, M., Widmann, C., Maillard, A., Miklossy, J., Dina, C., Hani, E.H., Vionnet, N., Nicod, P., Boutin, P., Froguel, P. Nat. Genet. (2000)
- Cdk5-dependent regulation of glucose-stimulated insulin secretion. Wei, F.Y., Nagashima, K., Ohshima, T., Saheki, Y., Lu, Y.F., Matsushita, M., Yamada, Y., Mikoshiba, K., Seino, Y., Matsui, H., Tomizawa, K. Nat. Med. (2005)
- Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor. Inagaki, N., Gonoi, T., Clement, J.P., Namba, N., Inazawa, J., Gonzalez, G., Aguilar-Bryan, L., Seino, S., Bryan, J. Science (1995)
- Cytotoxic autoantibodies to beta cells in the serum of patients with insulin-dependent diabetes mellitus. Dobersen, M.J., Scharff, J.E., Ginsberg-Fellner, F., Notkins, A.L. N. Engl. J. Med. (1980)
- CTLA-4-Ig regulates tryptophan catabolism in vivo. Grohmann, U., Orabona, C., Fallarino, F., Vacca, C., Calcinaro, F., Falorni, A., Candeloro, P., Belladonna, M.L., Bianchi, R., Fioretti, M.C., Puccetti, P. Nat. Immunol. (2002)
- Phenotypic and functional analysis of CD8(+) T cells undergoing peripheral deletion in response to cross-presentation of self-antigen. Hernandez, J., Aung, S., Redmond, W.L., Sherman, L.A. J. Exp. Med. (2001)
- Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats. Nie, Y., Nakashima, M., Brubaker, P.L., Li, Q.L., Perfetti, R., Jansen, E., Zambre, Y., Pipeleers, D., Friedman, T.C. J. Clin. Invest. (2000)
- Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus. Seufert, J., Weir, G.C., Habener, J.F. J. Clin. Invest. (1998)