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Gene Review:

AIS3 - autoimmune susceptibility 3 (vitiligo...

Homo sapiens

Tanaka, H. et al., Agran, P.F., Gales, H. et al., Dwyer, K.M. et al., Williams, M.

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Disease relevance of AIS3

The predominant form of head injury recorded was low severity concussion--AIS-1, AIS-2, AIS-3 [1].
RESULTS: A total of 1036 patients were eligible for entry into the trauma database; of these, 170 patients had chest and/or abdominal injuries coded as AIS 3 or more [2].

High impact information on AIS3

Although the injuries were predominantly minor (Abbreviated Injury Scale (AIS) 1), two children sustained moderate injury (AIS 2), and one child sustained severe injury (AIS 3) [3].
Most patients (79.1%) had AIS 3 or greater head or spinal cord injury as the primary diagnosis leading to tube placement [4].
CONCLUSION: The frequency of fungal infection onset was higher in patients with severe ISS of 16 or higher, those who used the ventilator, had inhalation injury, severe burns (BI>15), were in a coma, and had severe injury of lung parenchyme with chest AIS 3 or higher [5].

References

The protective performance of bicyclists' helmets in accidents. Williams, M. Accident; analysis and prevention. (1991) [Pubmed]
Is there a role for planned serial chest radiographs and abdominal ultrasound scans in the resuscitation room following trauma? Gales, H., Perry, M. Annals of the Royal College of Surgeons of England. (2006) [Pubmed]
Motor vehicle occupant injuries in noncrash events. Agran, P.F. Pediatrics (1981) [Pubmed]
Percutaneous endoscopic gastrostomy: the preferred method of elective feeding tube placement in trauma patients. Dwyer, K.M., Watts, D.D., Thurber, J.S., Benoit, R.S., Fakhry, S.M. The Journal of trauma. (2002) [Pubmed]
[Fungal infection in patients with serious disease. Risk analysis of fungal infection]. Tanaka, H., Huruhata, T., Gotou, H., Sakurai, M., Shimazaki, S. Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology. (1999) [Pubmed]

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