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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Craniocerebral Trauma

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Disease relevance of Craniocerebral Trauma


Psychiatry related information on Craniocerebral Trauma


High impact information on Craniocerebral Trauma


Chemical compound and disease context of Craniocerebral Trauma


Biological context of Craniocerebral Trauma


Anatomical context of Craniocerebral Trauma


Gene context of Craniocerebral Trauma

  • We report a prospective clinical study to test the hypothesis that patients with APOE epsilon4 have a worse clinical outcome 6 months after head injury than those without APOE epsilon4 [25].
  • A "paradoxical" response of GH to TRH was observed on the day after the head trauma (basal vs. peak, p = .002) but not on day 16 [30].
  • An elevated serum level of vWf may suggest endothelial activation in severe head injury [31].
  • The levels of serum TM and vWf appear to be good indicators of the cerebral endothelial injury and of endothelial activation in severe head injury [31].
  • Regarding severity and outcome, BDNF levels showed a sharp peak after head injury, but the only significant association was between NGF expression in the CSF and a good outcome versus a poor outcome ( p=0.007) [32].

Analytical, diagnostic and therapeutic context of Craniocerebral Trauma


  1. Concentration of 3', 5' cyclic adenosine monophosphate in ventricular cerebrospinal fluid of patients with prolonged coma after head trauma or intracranial hemorrhage. Rudman, D., Fleischer, A., Kutner, M.H. N. Engl. J. Med. (1976) [Pubmed]
  2. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Bruce, A.J., Boling, W., Kindy, M.S., Peschon, J., Kraemer, P.J., Carpenter, M.K., Holtsberg, F.W., Mattson, M.P. Nat. Med. (1996) [Pubmed]
  3. Postoperative epilepsy: a double-blind trial of phenytoin after craniotomy. North, J.B., Penhall, R.K., Hanieh, A., Hann, C.S., Challen, R.G., Frewin, D.B. Lancet (1980) [Pubmed]
  4. Signs of central nervous system dysfunction in obsessive-compulsive disorder. Hollander, E., Schiffman, E., Cohen, B., Rivera-Stein, M.A., Rosen, W., Gorman, J.M., Fyer, A.J., Papp, L., Liebowitz, M.R. Arch. Gen. Psychiatry (1990) [Pubmed]
  5. Hyponatremia responsive to fludrocortisone acetate in elderly patients after head injury. Ishikawa, S.E., Saito, T., Kaneko, K., Okada, K., Kuzuya, T. Ann. Intern. Med. (1987) [Pubmed]
  6. Assessment of competency: the role of neurobehavioral deficits. Freedman, M., Stuss, D.T., Gordon, M. Ann. Intern. Med. (1991) [Pubmed]
  7. Severe episodic neurological deficits and permanent mental retardation in a child with a novel FHM2 ATP1A2 mutation. Vanmolkot, K.R., Stroink, H., Koenderink, J.B., Kors, E.E., van den Heuvel, J.J., van den Boogerd, E.H., Stam, A.H., Haan, J., De Vries, B.B., Terwindt, G.M., Frants, R.R., Ferrari, M.D., van den Maagdenberg, A.M. Ann. Neurol. (2006) [Pubmed]
  8. The NMDA receptor NR2B subunit: a valid therapeutic target for multiple CNS pathologies. Chazot, P.L. Current medicinal chemistry. (2004) [Pubmed]
  9. Synergistic inhibitory effect of ascorbic acid and acetylsalicylic acid on prostaglandin E2 release in primary rat microglia. Fiebich, B.L., Lieb, K., Kammerer, N., Hüll, M. J. Neurochem. (2003) [Pubmed]
  10. Brain SPECT in neurology and psychiatry. Camargo, E.E. J. Nucl. Med. (2001) [Pubmed]
  11. Indications for computed tomography in patients with minor head injury. Haydel, M.J., Preston, C.A., Mills, T.J., Luber, S., Blaudeau, E., DeBlieux, P.M. N. Engl. J. Med. (2000) [Pubmed]
  12. A randomized, double-blind study of phenytoin for the prevention of post-traumatic seizures. Temkin, N.R., Dikmen, S.S., Wilensky, A.J., Keihm, J., Chabal, S., Winn, H.R. N. Engl. J. Med. (1990) [Pubmed]
  13. Lesion-induced axonal sprouting and hyperexcitability in the hippocampus in vitro: implications for the genesis of posttraumatic epilepsy. McKinney, R.A., Debanne, D., Gähwiler, B.H., Thompson, S.M. Nat. Med. (1997) [Pubmed]
  14. Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury. Nicoll, J.A., Roberts, G.W., Graham, D.I. Nat. Med. (1995) [Pubmed]
  15. Sedation in the intensive care unit: a systematic review. Ostermann, M.E., Keenan, S.P., Seiferling, R.A., Sibbald, W.J. JAMA (2000) [Pubmed]
  16. Effects of pegorgotein on neurologic outcome of patients with severe head injury. A multicenter, randomized controlled trial. Young, B., Runge, J.W., Waxman, K.S., Harrington, T., Wilberger, J., Muizelaar, J.P., Boddy, A., Kupiec, J.W. JAMA (1996) [Pubmed]
  17. Phencyclidine abuse mimicking head injury. Corales, R.L., Maull, K.I., Becker, D.P. JAMA (1980) [Pubmed]
  18. Decrease in glutamate in the jugular vein after head injury. Kudo, A., Suzuki, M., Kitakami, A., Kuroda, K., Ogawa, A. Lancet (1995) [Pubmed]
  19. Propofol use in head-injury patients. Myburgh, J.A., Upton, R.N. Lancet (2001) [Pubmed]
  20. Avoidable factors contributing to the death of head injury patients in general hospitals in Mersey Region. Jeffreys, R.V., Jones, J.J. Lancet (1981) [Pubmed]
  21. Childhood head injury and expression of schizophrenia in multiply affected families. AbdelMalik, P., Husted, J., Chow, E.W., Bassett, A.S. Arch. Gen. Psychiatry (2003) [Pubmed]
  22. Neuroprotection by the inhibition of apoptosis. Robertson, G.S., Crocker, S.J., Nicholson, D.W., Schulz, J.B. Brain Pathol. (2000) [Pubmed]
  23. Specific kinetic alterations of human CaV2.1 calcium channels produced by mutation S218L causing familial hemiplegic migraine and delayed cerebral edema and coma after minor head trauma. Tottene, A., Pivotto, F., Fellin, T., Cesetti, T., van den Maagdenberg, A.M., Pietrobon, D. J. Biol. Chem. (2005) [Pubmed]
  24. Head injury and the risk of AD in the MIRAGE study. Guo, Z., Cupples, L.A., Kurz, A., Auerbach, S.H., Volicer, L., Chui, H., Green, R.C., Sadovnick, A.D., Duara, R., DeCarli, C., Johnson, K., Go, R.C., Growdon, J.H., Haines, J.L., Kukull, W.A., Farrer, L.A. Neurology (2000) [Pubmed]
  25. Association of apolipoprotein E polymorphism with outcome after head injury. Teasdale, G.M., Nicoll, J.A., Murray, G., Fiddes, M. Lancet (1997) [Pubmed]
  26. Cortical cell death induced by IL-1 is mediated via actions in the hypothalamus of the rat. Allan, S.M., Parker, L.C., Collins, B., Davies, R., Luheshi, G.N., Rothwell, N.J. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  27. Development of fetal hippocampal grafts in intact and lesioned hippocampus. Shetty, A.K., Turner, D.A. Prog. Neurobiol. (1996) [Pubmed]
  28. Creatine kinase BB isoenzyme levels by radioimmunoassay in patients with neurological disease. Bell, R.D., Rosenberg, R.N., Ting, R., Mukherjee, A., Stone, M.J., Willerson, J.T. Ann. Neurol. (1978) [Pubmed]
  29. Ciprofloxacin in the treatment of gram-negative bacillary meningitis. Schönwald, S., Beus, I., Lisić, M., Car, V., Gmajnicki, B. Am. J. Med. (1989) [Pubmed]
  30. Provocative hypothalamopituitary axis tests in severe head injury: correlations with severity and prognosis. Della Corte, F., Mancini, A., Valle, D., Gallizzi, F., Carducci, P., Mignani, V., De Marinis, L. Crit. Care Med. (1998) [Pubmed]
  31. Cerebral endothelial injury in severe head injury: the significance of measurements of serum thrombomodulin and the von Willebrand factor. Yokota, H., Naoe, Y., Nakabayashi, M., Unemoto, K., Kushimoto, S., Kurokawa, A., Node, Y., Yamamoto, Y. J. Neurotrauma (2002) [Pubmed]
  32. Correlation between neurotrophic factor expression and outcome of children with severe traumatic brain injury. Chiaretti, A., Piastra, M., Polidori, G., Di Rocco, C., Caresta, E., Antonelli, A., Amendola, T., Aloe, L. Intensive care medicine. (2003) [Pubmed]
  33. Neuronal death enhanced by N-methyl-D-aspartate antagonists. Ikonomidou, C., Stefovska, V., Turski, L. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  34. Monitoring of cerebral autoregulation in head-injured patients. Czosnyka, M., Smielewski, P., Kirkpatrick, P., Menon, D.K., Pickard, J.D. Stroke (1996) [Pubmed]
  35. Prediction of psychiatric morbidity in severely injured accident victims at one-year follow-up. Schnyder, U., Moergeli, H., Trentz, O., Klaghofer, R., Buddeberg, C. Am. J. Respir. Crit. Care Med. (2001) [Pubmed]
  36. Uncoupling of cerebral blood flow and metabolism after cerebral contusion in the rat. Richards, H.K., Simac, S., Piechnik, S., Pickard, J.D. J. Cereb. Blood Flow Metab. (2001) [Pubmed]
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