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Gene Review

slbo  -  slow border cells

Drosophila melanogaster

Synonyms: C/EBP, CCAAT/enhancer-binding protein, CG4354, DC/EBP, Dm-c/EBP, ...
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High impact information on slbo


Biological context of slbo

  • Timely initiation of border cell migration requires the product of the slow border cells (slbo) locus, which encodes the Drosophila homolog of the transcription factor C/EBP [4].
  • Here we identify Drosophila Stat92E (signal transducer and activator of transcription) in a screen for gain-of-function suppressors of the slbo mutant phenotype [5].
  • This fragment also contained three potential half-nuclear factor 1 (NF1) sites (TGGA-NNNNNGCCA) and a putative CCAAT-enhancer binding protein (C/EBP) binding site [6].

Other interactions of slbo

  • Furthermore, C/EBP-independent btl expression was able to rescue the migration defects of hypomorphic slbo alleles [4].


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