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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

foi  -  fear-of-intimacy

Drosophila melanogaster

Synonyms: CG6817, Dmel\CG6817, FOI, Protein fear-of-intimacy, Protein kastchen, ...
 
 
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High impact information on foi

  • We further show that expression of DE-cadherin in the gonad is regulated post-transcriptionally and that foi affects this post-transcriptional control [1].
  • Kastchen corresponds to the recently described gene fear-of-intimacy (foi) that was identified in screen for genes affecting germ cell migration, suggesting that Foi-Kastchen is more generally involved in regulating cell migration [2].
  • The Drosophila transmembrane protein Fear-of-intimacy controls glial cell migration [2].

References

  1. Zinc transport activity of Fear of Intimacy is essential for proper gonad morphogenesis and DE-cadherin expression. Mathews, W.R., Ong, D., Milutinovich, A.B., Van Doren, M. Development (2006) [Pubmed]
  2. The Drosophila transmembrane protein Fear-of-intimacy controls glial cell migration. Pielage, J., Kippert, A., Zhu, M., Klämbt, C. Dev. Biol. (2004) [Pubmed]
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