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Gene Review

casq1  -  calsequestrin 1 (fast-twitch, skeletal...

Xenopus (Silurana) tropicalis

Synonyms: casq, pdib1
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Disease relevance of casq1

  • Calsequestrin is one of several affected genes that encode proteins involved in calcium sequestration, transport and utilization in muscle suggesting that uncontrolled calcium influx into the growing limb muscle fibers causes rhabdomyolysis [1].

High impact information on casq1


  1. Changing a limb muscle growth program into a resorption program. Cai, L., Das, B., Brown, D.D. Dev. Biol. (2007) [Pubmed]
  2. Presence of inositol 1,4,5-trisphosphate receptor, calreticulin, and calsequestrin in eggs of sea urchins and Xenopus laevis. Parys, J.B., McPherson, S.M., Mathews, L., Campbell, K.P., Longo, F.J. Dev. Biol. (1994) [Pubmed]
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