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Gene Review:

casq1 - calsequestrin 1 (fast-twitch, skeletal...

Xenopus (Silurana) tropicalis

Synonyms: casq, pdib1

Parys, J.B. et al., Cai, L. et al.

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Disease relevance of casq1

Calsequestrin is one of several affected genes that encode proteins involved in calcium sequestration, transport and utilization in muscle suggesting that uncontrolled calcium influx into the growing limb muscle fibers causes rhabdomyolysis [1].

High impact information on casq1

The distribution of calreticulin and calsequestrin in both sea urchin and Xenopus oocytes and eggs was similar to that observed for the InsP3R [2].
Presence of inositol 1,4,5-trisphosphate receptor, calreticulin, and calsequestrin in eggs of sea urchins and Xenopus laevis [2].

References

Changing a limb muscle growth program into a resorption program. Cai, L., Das, B., Brown, D.D. Dev. Biol. (2007) [Pubmed]
Presence of inositol 1,4,5-trisphosphate receptor, calreticulin, and calsequestrin in eggs of sea urchins and Xenopus laevis. Parys, J.B., McPherson, S.M., Mathews, L., Campbell, K.P., Longo, F.J. Dev. Biol. (1994) [Pubmed]

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CASQ1	Bos taurus
csq-1	Caenorhabditis elegans
CASQ1	Canis lupus familiaris
casq1b	Danio rerio
casq1a	Danio rerio
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Casq1	Mus musculus
CASQ1	Pan troglodytes
Casq1	Rattus norvegicus

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