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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

sparc  -  secreted protein, acidic, cysteine-rich...

Xenopus (Silurana) tropicalis

 
 
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High impact information on sparc

  • In Xenopus laevis embryos, SPARC is expressed first by dorsal mesoderm cells at the end of gastrulation and undergoes complex, rapid changes in its pattern of expression during early organogenesis [1].
  • In Xenopus, SPARC transcripts are first expressed by primordial cells which give rise to the first embryonic tissues, the notochord and somites [2].

References

  1. A calcium-binding motif in SPARC/osteonectin inhibits chordomesoderm cell migration during Xenopus laevis gastrulation: evidence of counter-adhesive activity in vivo. Huynh, M.H., Sage, E.H., Ringuette, M. Dev. Growth Differ. (1999) [Pubmed]
  2. Transient expression of SPARC in the dorsal axis of early Xenopus embryos: correlation with calcium-dependent adhesion and electrical coupling. Damjanovski, S., Malaval, L., Ringuette, M.J. Int. J. Dev. Biol. (1994) [Pubmed]
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