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Gene Review:

FTL_1637 - lipoprotein

Francisella tularensis subsp. holarctica LVS

Scoles, G.A., Golovliov, I. et al., Lamps, L.W. et al., Sjöstedt, A. et al.

Lamps, Havens, Sjostedt, Page, Scott, Sjöstedt, Eriksson, Berglund, Tärnvik, Scoles,

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Disease relevance of FTL_1637

PCR analysis for a 211-bp fragment of the FT lipoprotein gene was performed on tissues from 16 cases of tularemia [1].
Adjuvanticity of ISCOMs incorporating a T cell-reactive lipoprotein of the facultative intracellular pathogen Francisella tularensis [2].
Several ticks were co-infected, either with two FLE with divergent 17-kDa lipoprotein gene sequences or with FLE and an unidentified species of spotted fever group rickettsia (alpha-proteobacteria) [3].

High impact information on FTL_1637

The DNA was detected by multiplex PCR targeting the 16S rRNA gene and a 17-kDa lipoprotein gene of F. tularensis [4].

References

Histologic and molecular diagnosis of tularemia: a potential bioterrorism agent endemic to North America. Lamps, L.W., Havens, J.M., Sjostedt, A., Page, D.L., Scott, M.A. Mod. Pathol. (2004) [Pubmed]
Adjuvanticity of ISCOMs incorporating a T cell-reactive lipoprotein of the facultative intracellular pathogen Francisella tularensis. Golovliov, I., Ericsson, M., Akerblom, L., Sandström, G., Tärnvik, A., Sjöstedt, A. Vaccine (1995) [Pubmed]
Phylogenetic analysis of the Francisella-like endosymbionts of Dermacentor ticks. Scoles, G.A. J. Med. Entomol. (2004) [Pubmed]
Detection of Francisella tularensis in ulcers of patients with tularemia by PCR. Sjöstedt, A., Eriksson, U., Berglund, L., Tärnvik, A. J. Clin. Microbiol. (1997) [Pubmed]

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