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Gene Review:

XIAP - X-linked inhibitor of apoptosis

Gallus gallus

Synonyms: BIRC4, IAP3

McKinnon, S.J. et al.

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High impact information on BIRC4

Gene therapy delivering BIRC4 significantly promoted optic nerve axon survival in a chronic ocular hypertensive model of rat glaucoma [1].

Biological context of BIRC4

After chronic exposure to elevated intraocular pressure, we performed optic nerve axon counts to determine the neuroprotective effects of retinal BIRC4 expression, and compared axon survival with vector and balanced salt solution control groups [1].

References

Baculoviral IAP repeat-containing-4 protects optic nerve axons in a rat glaucoma model. McKinnon, S.J., Lehman, D.M., Tahzib, N.G., Ransom, N.L., Reitsamer, H.A., Liston, P., LaCasse, E., Li, Q., Korneluk, R.G., Hauswirth, W.W. Mol. Ther. (2002) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

IAP4	Anopheles gambiae str. PEST
IAP3	Anopheles gambiae str. PEST
AgaP_AGAP012677	Anopheles gambiae str. PEST
IAP7	Anopheles gambiae str. PEST
XIAP	Bos taurus
XIAP	Canis lupus familiaris
xiap	Danio rerio
XIAP	Homo sapiens
Xiap	Mus musculus
XIAP	Pan troglodytes
Xiap	Rattus norvegicus
xiap	Xenopus (Silurana) tropicalis

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