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MeSH Review

Intraocular Pressure

 
 
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Disease relevance of Intraocular Pressure

 

Psychiatry related information on Intraocular Pressure

 

High impact information on Intraocular Pressure

 

Chemical compound and disease context of Intraocular Pressure

 

Biological context of Intraocular Pressure

 

Anatomical context of Intraocular Pressure

 

Associations of Intraocular Pressure with chemical compounds

 

Gene context of Intraocular Pressure

  • Carbonic anhydrase (CA) activity plays an important role in controlling aqueous humor production in the eye and in regulating intraocular pressure [31].
  • In addition, APOE(-491T), interacting at a highly significant level with an SNP in the MYOC promoter, MYOC(-1000G), is associated with increased intraocular pressure (IOP) and with limited effectiveness of IOP-lowering treatments in patients with POAG [32].
  • However, because humans with defective AQP1 are phenotypically normal and because the ocular application of phorbol esters reduce intraocular pressure, we postulated that the water channel activity of AQP4 may be regulated by these agents [33].
  • Although ET-1-induced PG release could function to modulate, through cAMP, the responses to muscarinic receptor stimulation, the precise role of these effects in intraocular pressure lowering and accommodation remains to be delineated [34].
  • The present study tested whether OPTN sequence changes play a role in early-onset glaucoma characterized by elevated intraocular pressure [35].
 

Analytical, diagnostic and therapeutic context of Intraocular Pressure

References

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  23. Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor. Jacobson, N., Andrews, M., Shepard, A.R., Nishimura, D., Searby, C., Fingert, J.H., Hageman, G., Mullins, R., Davidson, B.L., Kwon, Y.H., Alward, W.L., Stone, E.M., Clark, A.F., Sheffield, V.C. Hum. Mol. Genet. (2001) [Pubmed]
  24. Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma. Schlötzer-Schrehardt, U., Zenkel, M., Decking, U., Haubs, D., Kruse, F.E., Jünemann, A., Coca-Prados, M., Naumann, G.O. Invest. Ophthalmol. Vis. Sci. (2005) [Pubmed]
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  29. Functional characterization of the ocular prostaglandin f2alpha (PGF2alpha) receptor. Activation by the isoprostane, 12-iso-PGF2alpha. Kunapuli, P., Lawson, J.A., Rokach, J., FitzGerald, G.A. J. Biol. Chem. (1997) [Pubmed]
  30. Heparin II domain of fibronectin uses alpha4beta1 integrin to control focal adhesion and stress fiber formation, independent of syndecan-4. Peterson, J.A., Sheibani, N., David, G., Garcia-Pardo, A., Peters, D.M. J. Biol. Chem. (2005) [Pubmed]
  31. Localization of carbonic anhydrase IV in a specific capillary bed of the human eye. Hageman, G.S., Zhu, X.L., Waheed, A., Sly, W.S. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  32. Apolipoprotein E-promoter single-nucleotide polymorphisms affect the phenotype of primary open-angle glaucoma and demonstrate interaction with the myocilin gene. Copin, B., Brézin, A.P., Valtot, F., Dascotte, J.C., Béchetoille, A., Garchon, H.J. Am. J. Hum. Genet. (2002) [Pubmed]
  33. Regulation of aquaporin-4 water channels by phorbol ester-dependent protein phosphorylation. Han, Z., Wax, M.B., Patil, R.V. J. Biol. Chem. (1998) [Pubmed]
  34. Prostaglandins mediate the stimulatory effects of endothelin-1 on cyclic adenosine monophosphate accumulation in ciliary smooth muscle isolated from bovine, cat, and other mammalian species. Abdel-Latif, A.A., Yousufzai, S.Y., el-Mowafy, A.M., Ye, Z. Invest. Ophthalmol. Vis. Sci. (1996) [Pubmed]
  35. Defining the pathogenicity of optineurin in juvenile open-angle glaucoma. Willoughby, C.E., Chan, L.L., Herd, S., Billingsley, G., Noordeh, N., Levin, A.V., Buys, Y., Trope, G., Sarfarazi, M., Héon, E. Invest. Ophthalmol. Vis. Sci. (2004) [Pubmed]
  36. Essential fatty acid deficiency in total parenteral nutrition. Detection by changes in intraocular pressure. Freund, H., Floman, N., Schwartz, B., Fischer, J.E. Ann. Surg. (1979) [Pubmed]
  37. Vanadate and aqueous humor dynamics. Proctor Lecture. Becker, B. Invest. Ophthalmol. Vis. Sci. (1980) [Pubmed]
  38. Uveoscleral aqueous outflow in the rhesus monkey: importance of uveal reabsorption. Pederson, J.E., Gaasterland, D.E., MacLellan, H.M. Invest. Ophthalmol. Vis. Sci. (1977) [Pubmed]
  39. Variability in choriocapillaris blood flow distribution. Flower, R.W., Fryczkowski, A.W., McLeod, D.S. Invest. Ophthalmol. Vis. Sci. (1995) [Pubmed]
  40. Tonometric changes of latanoprost-induced intraocular pressure reduction after photorefractive keratectomy. Tamburrelli, C., Vaiano, A.S., Salgarello, T., Caputo, C.G., Scullica, L. Invest. Ophthalmol. Vis. Sci. (2004) [Pubmed]
 
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