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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

EFNA2  -  ephrin-A2

Gallus gallus

 
 
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High impact information on ELF-1

  • Our results show that the rostral portion of the tectum adopts a caudal phenotype: the gradient of cytoarchitectonic differentiation is abolished, and the molecular markers RAGS and ELF-1 are strongly expressed rostrally [1].
  • Here we show that the ligands RAGS and ELF-1 were expressed in limb buds and that they activated Cek8 when presented in membrane-bound or clustered forms of Fc chimeric proteins but not in unclustered soluble forms [2].
  • The inhibitory effect on neurite outgrowth of motoneurons exerted by the ligands ELF-1 and RAGS [2].

References

  1. Rostral optic tectum acquires caudal characteristics following ectopic engrailed expression. Logan, C., Wizenmann, A., Drescher, U., Monschau, B., Bonhoeffer, F., Lumsden, A. Curr. Biol. (1996) [Pubmed]
  2. The inhibitory effect on neurite outgrowth of motoneurons exerted by the ligands ELF-1 and RAGS. Ohta, K., Iwamasa, H., Drescher, U., Terasaki, H., Tanaka, H. Mech. Dev. (1997) [Pubmed]
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