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Gene Review

slpA  -  peptidyl-prolyl cis- trans isomerase

Escherichia coli UTI89

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High impact information on slpA

  • The expression of beta-galactosidase from a lac transcriptional fusion to slpA is increased six- to eightfold when the alpA+ gene is present on a multicopy plasmid [1].
  • We have used Tn10 and lambda placMu mutagenesis to identify a chromosomal locus, slpA, that is required for alpA+ suppression of delta lon [1].


  1. Alp suppression of Lon: dependence on the slpA gene. Trempy, J.E., Kirby, J.E., Gottesman, S. J. Bacteriol. (1994) [Pubmed]
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