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Gene Review:

Pitslre - CG4268 gene product from transcript CG4268-RA

Drosophila melanogaster

Synonyms: CG4268, Cell division cycle 2-like, Dmel\CG4268, Gat, Gta, ...

Baimai, V. et al., Koken, M.H. et al.

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Disease relevance of Pitslre

Microinjection and DNA transfection of ERCC3Dm into human xeroderma pigmentosum (c.g. B) fibroblasts and group 3 rodent mutants did not yield detectable correction [1].

High impact information on Pitslre

Group 3 comprises species D, which is characterized by conspicuous blocks of pericentric heterochromatin in all autosomes but the long arm of the subtelocentric X chromosome is euchromatic and lacks a major portion of centromeric heterochromatin [2].

References

Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3. Koken, M.H., Vreeken, C., Bol, S.A., Cheng, N.C., Jaspers-Dekker, I., Hoeijmakers, J.H., Eeken, J.C., Weeda, G., Pastink, A. Nucleic Acids Res. (1992) [Pubmed]
Metaphase karyotypes of fruit flies of Thailand. I. Five sibling species of the Bactrocera dorsalis complex. Baimai, V., Trinachartvanit, W., Tigvattananont, S., Grote, P.J., Poramarcom, R., Kijchalao, U. Genome (1995) [Pubmed]

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