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Gene Review

slc31a1  -  solute carrier family 31 (copper...

Danio rerio

Synonyms: SO:0000704, ctr-1, ctr1, zgc:76839
 
 
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High impact information on slc31a1

  • Despite the existence of at least one other copper transport mechanism in the fish, our studies show that zebrafish ctr1 is an essential gene for development [1].
  • Defects include cell death in tissues where ctr1 is most heavily expressed, a finding similar to that described for a mouse knockout of mCtr1 [1].
  • We find only a single ctr1 gene in the zebrafish genome which maps to linkage group 5 [1].
  • The genomic structure of the zebrafish gene shows that it consists of five exons and that exon-intron boundaries are absolutely conserved with the mammalian ctr1 genes [1].

References

 
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