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Gene Review

TYR  -  tyrosinase (oculocutaneous albinism IA)

Canis lupus familiaris

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High impact information on TYR


Analytical, diagnostic and therapeutic context of TYR

  • We used PCR amplification of cDNA prepared from skin biopsies to determine the full-length protein-coding sequence of tyrosinase ( TYR) in cattle of several coat colors [2].


  1. Linkage mapping of TYR to dog chromosome 21. Schmidtz, B.H., Schmutz, S.M. Anim. Genet. (2002) [Pubmed]
  2. A form of albinism in cattle is caused by a tyrosinase frameshift mutation. Schmutz, S.M., Berryere, T.G., Ciobanu, D.C., Mileham, A.J., Schmidtz, B.H., Fredholm, M. Mamm. Genome (2004) [Pubmed]
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