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Gene Review:

GNAT1 - guanine nucleotide binding protein (G...

Canis lupus familiaris

Ray, K. et al., Ray, K. et al., Brouillette, J.A. et al.

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Disease relevance of GNAT1

Sequence information of canine GNAT1 gene will enable testing this locus as a candidate in other canine hereditary retinal degenerations [1].

High impact information on GNAT1

Tth111I PCR/RFLP marker in the canine rod transducin alpha (GNAT1) gene [2].
Canine GNAT1 cDNA was cloned and sequenced after reverse transcription (RT) and polymerase chain reaction (PCR) of total retinal RNA, and PCR amplification of specific sequences from a canine retinal cDNA library [1].

Biological context of GNAT1

A highly polymorphic RFLP marker in the canine transducin alpha-1 subunit gene (GNAT1) [3].

References

Canine rod transducin alpha-1: cloning of the cDNA and evaluation of the gene as a candidate for progressive retinal atrophy. Ray, K., Baldwin, V.J., Zeiss, C., Acland, G.M., Aguirre, G.D. Curr. Eye Res. (1997) [Pubmed]
Tth111I PCR/RFLP marker in the canine rod transducin alpha (GNAT1) gene. Brouillette, J.A., Venta, P.J. Anim. Genet. (2000) [Pubmed]
A highly polymorphic RFLP marker in the canine transducin alpha-1 subunit gene (GNAT1). Ray, K., Zeiss, C., Acland, G.M., Trepanier, L.A., Aguirre, G.D. Anim. Genet. (1996) [Pubmed]

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GNAT1	Bos taurus
gnat1	Danio rerio
GNAT1	Gallus gallus
GNAT1	Homo sapiens
GNAT1	Macaca mulatta
Gnat1	Mus musculus
GNAT1	Pan troglodytes
Gnat1	Rattus norvegicus
gnat1	Xenopus (Silurana) tropicalis

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