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MeSH Review

Retinal Degeneration

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Disease relevance of Retinal Degeneration


Psychiatry related information on Retinal Degeneration


High impact information on Retinal Degeneration


Chemical compound and disease context of Retinal Degeneration


Biological context of Retinal Degeneration


Anatomical context of Retinal Degeneration


Gene context of Retinal Degeneration


Analytical, diagnostic and therapeutic context of Retinal Degeneration


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  3. Rapid cloning of expanded trinucleotide repeat sequences from genomic DNA. Koob, M.D., Benzow, K.A., Bird, T.D., Day, J.W., Moseley, M.L., Ranum, L.P. Nat. Genet. (1998) [Pubmed]
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  10. Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa. Gal, A., Li, Y., Thompson, D.A., Weir, J., Orth, U., Jacobson, S.G., Apfelstedt-Sylla, E., Vollrath, D. Nat. Genet. (2000) [Pubmed]
  11. Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice. Weng, J., Mata, N.L., Azarian, S.M., Tzekov, R.T., Birch, D.G., Travis, G.H. Cell (1999) [Pubmed]
  12. Positional cloning of the gene for X-linked retinitis pigmentosa 2. Schwahn, U., Lenzner, S., Dong, J., Feil, S., Hinzmann, B., van Duijnhoven, G., Kirschner, R., Hemberger, M., Bergen, A.A., Rosenberg, T., Pinckers, A.J., Fundele, R., Rosenthal, A., Cremers, F.P., Ropers, H.H., Berger, W. Nat. Genet. (1998) [Pubmed]
  13. Mutation of the gene encoding cellular retinaldehyde-binding protein in autosomal recessive retinitis pigmentosa. Maw, M.A., Kennedy, B., Knight, A., Bridges, R., Roth, K.E., Mani, E.J., Mukkadan, J.K., Nancarrow, D., Crabb, J.W., Denton, M.J. Nat. Genet. (1997) [Pubmed]
  14. Mice lacking ornithine-delta-aminotransferase have paradoxical neonatal hypoornithinaemia and retinal degeneration. Wang, T., Lawler, A.M., Steel, G., Sipila, I., Milam, A.H., Valle, D. Nat. Genet. (1995) [Pubmed]
  15. Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias. Trottier, Y., Lutz, Y., Stevanin, G., Imbert, G., Devys, D., Cancel, G., Saudou, F., Weber, C., David, G., Tora, L. Nature (1995) [Pubmed]
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  18. Light adaptation through phosphoinositide-regulated translocation of Drosophila visual arrestin. Lee, S.J., Xu, H., Kang, L.W., Amzel, L.M., Montell, C. Neuron (2003) [Pubmed]
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  20. Regulation of phototransduction responsiveness and retinal degeneration by a phospholipase D-generated signaling lipid. LaLonde, M.M., Janssens, H., Rosenbaum, E., Choi, S.Y., Gergen, J.P., Colley, N.J., Stark, W.S., Frohman, M.A. J. Cell Biol. (2005) [Pubmed]
  21. AIF deficiency compromises oxidative phosphorylation. Vahsen, N., Candé, C., Brière, J.J., Bénit, P., Joza, N., Larochette, N., Mastroberardino, P.G., Pequignot, M.O., Casares, N., Lazar, V., Feraud, O., Debili, N., Wissing, S., Engelhardt, S., Madeo, F., Piacentini, M., Penninger, J.M., Schägger, H., Rustin, P., Kroemer, G. EMBO J. (2004) [Pubmed]
  22. The retinitis pigmentosa GTPase regulator, RPGR, interacts with the delta subunit of rod cyclic GMP phosphodiesterase. Linari, M., Ueffing, M., Manson, F., Wright, A., Meitinger, T., Becker, J. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  23. Morphological, physiological, and biochemical changes in rhodopsin knockout mice. Lem, J., Krasnoperova, N.V., Calvert, P.D., Kosaras, B., Cameron, D.A., Nicolò, M., Makino, C.L., Sidman, R.L. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  24. Mkks-null mice have a phenotype resembling Bardet-Biedl syndrome. Fath, M.A., Mullins, R.F., Searby, C., Nishimura, D.Y., Wei, J., Rahmouni, K., Davis, R.E., Tayeh, M.K., Andrews, M., Yang, B., Sigmund, C.D., Stone, E.M., Sheffield, V.C. Hum. Mol. Genet. (2005) [Pubmed]
  25. Folding and subunit assembly of photoreceptor peripherin/rds is mediated by determinants within the extracellular/intradiskal EC2 domain: implications for heterogeneous molecular pathologies. Goldberg, A.F., Fales, L.M., Hurley, J.B., Khattree, N. J. Biol. Chem. (2001) [Pubmed]
  26. The C terminus of peripherin/rds participates in rod outer segment targeting and alignment of disk incisures. Tam, B.M., Moritz, O.L., Papermaster, D.S. Mol. Biol. Cell (2004) [Pubmed]
  27. Generation of activated sialoadhesin-positive microglia during retinal degeneration. Hughes, E.H., Schlichtenbrede, F.C., Murphy, C.C., Sarra, G.M., Luthert, P.J., Ali, R.R., Dick, A.D. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  28. Night blindness in Sorsby's fundus dystrophy reversed by vitamin A. Jacobson, S.G., Cideciyan, A.V., Regunath, G., Rodriguez, F.J., Vandenburgh, K., Sheffield, V.C., Stone, E.M. Nat. Genet. (1995) [Pubmed]
  29. A candidate gene for the mouse mutation tubby. Noben-Trauth, K., Naggert, J.K., North, M.A., Nishina, P.M. Nature (1996) [Pubmed]
  30. Photoreceptor deactivation and retinal degeneration mediated by a photoreceptor-specific protein kinase C. Smith, D.P., Ranganathan, R., Hardy, R.W., Marx, J., Tsuchida, T., Zuker, C.S. Science (1991) [Pubmed]
  31. Rhodopsin activation causes retinal degeneration in Drosophila rdgC mutant. Steele, F., O'Tousa, J.E. Neuron (1990) [Pubmed]
  32. Correction of ornithine accumulation prevents retinal degeneration in a mouse model of gyrate atrophy of the choroid and retina. Wang, T., Steel, G., Milam, A.H., Valle, D. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  33. Pathology of Berkeley sickle cell mice: similarities and differences with human sickle cell disease. Manci, E.A., Hillery, C.A., Bodian, C.A., Zhang, Z.G., Lutty, G.A., Coller, B.S. Blood (2006) [Pubmed]
  34. Retinitis pigmentosa. Animal model: hereditary retinal degeneration in Wag/Rij rats. Lai, Y.L., Jacoby, R.O., Jensen, J.T., Yao, P.C. Am. J. Pathol. (1980) [Pubmed]
  35. Light-driven retinal ganglion cell responses in blind rd mice after neural retinal transplantation. Radner, W., Sadda, S.R., Humayun, M.S., Suzuki, S., Melia, M., Weiland, J., de Juan, E. Invest. Ophthalmol. Vis. Sci. (2001) [Pubmed]
  36. Tubby-like protein 1 homozygous splice-site mutation causes early-onset severe retinal degeneration. Lewis, C.A., Batlle, I.R., Batlle, K.G., Banerjee, P., Cideciyan, A.V., Huang, J., Alemán, T.S., Huang, Y., Ott, J., Gilliam, T.C., Knowles, J.A., Jacobson, S.G. Invest. Ophthalmol. Vis. Sci. (1999) [Pubmed]
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