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Gene Review:

Cont - Contactin

Drosophila melanogaster

Synonyms: CG1084, CONT, CT1481, D-Axonin, DCONT, ...

Banerjee, S. et al., Faivre-Sarrailh, C. et al.

Faivre-Sarrailh, Banerjee, Li, Hortsch, Laval, Bhat,

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High impact information on Cont

The cell-adhesion molecules NRX IV/Caspr/Paranodin (NCP1), contactin and Neurofascin-155 (NF-155) are all present at the vertebrate axo-glial SJs [1].
Interestingly, the murine homologs of Neurexin IV, Contactin, and Neuroglian are expressed at the paranodal SJs and play a key role in axon-glial interactions of myelinated axons [2].

Anatomical context of Cont

We also show that Neurexin IV, Contactin, and Neuroglian are coexpressed in the peripheral glial membranes and that these proteins exist as a complex in the Drosophila nervous system [2].

References

Drosophila contactin, a homolog of vertebrate contactin, is required for septate junction organization and paracellular barrier function. Faivre-Sarrailh, C., Banerjee, S., Li, J., Hortsch, M., Laval, M., Bhat, M.A. Development (2004) [Pubmed]
Axonal ensheathment and septate junction formation in the peripheral nervous system of Drosophila. Banerjee, S., Pillai, A.M., Paik, R., Li, J., Bhat, M.A. J. Neurosci. (2006) [Pubmed]

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IGL1	Anopheles gambiae str. PEST
CNTN3	Bos taurus
CNTN3	Canis lupus familiaris
LOC556251	Danio rerio
cntn3a.2	Danio rerio
CNTN3	Gallus gallus
CNTN3	Homo sapiens
CNTN3	Macaca mulatta
Cntn3	Mus musculus
CNTN3	Pan troglodytes
Cntn3	Rattus norvegicus

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