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Gene Review:

Art1 - Arginine methyltransferase 1

Drosophila melanogaster

Synonyms: CG6554, DART1, Dart, Dmel\CG6554, dart1

Boulanger, M.C. et al., Anne, J. et al.

Anne, Ollo, Ephrussi, Mechler,

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High impact information on Art1

Arginine methyltransferase Capsuleen is essential for methylation of spliceosomal Sm proteins and germ cell formation in Drosophila [1].
DART1 and DART4 have arginine methyltransferase activity towards substrates, including histones and RNA-binding proteins [2].
We identified a family of nine PRMTs (protein arginine methyltransferases) by sequence homology with mammalian arginine methyltransferases, which we have named DART1 to DART9 ( Drosophila arginine methyltransferases 1-9) [2].

Associations of Art1 with chemical compounds

Characterization of the Drosophila protein arginine methyltransferases DART1 and DART4 [2].

References

Arginine methyltransferase Capsuleen is essential for methylation of spliceosomal Sm proteins and germ cell formation in Drosophila. Anne, J., Ollo, R., Ephrussi, A., Mechler, B.M. Development (2007) [Pubmed]
Characterization of the Drosophila protein arginine methyltransferases DART1 and DART4. Boulanger, M.C., Miranda, T.B., Clarke, S., Di Fruscio, M., Suter, B., Lasko, P., Richard, S. Biochem. J. (2004) [Pubmed]

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