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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Ipp  -  Inositol polyphosphate 1-phosphatase

Drosophila melanogaster

Synonyms: CG3028, Dmel\CG3028, anon-WO02059370.48, ipp
 
 
 
 
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High impact information on Ipp

  • Synaptic defects and compensatory regulation of inositol metabolism in inositol polyphosphate 1-phosphatase mutants [1].
  • Notably, ipp mutants demonstrate compensatory upregulation of an alternative branch in the inositol-phosphate metabolism tree, thus providing a means of ensuring continued availability of inositol [1].
  • We demonstrate that ipp mutants have a defect in synaptic transmission resulting from a dramatic increase in the probability of vesicle release at larval neuromuscular junctions [1].

References

  1. Synaptic defects and compensatory regulation of inositol metabolism in inositol polyphosphate 1-phosphatase mutants. Acharya, J.K., Labarca, P., Delgado, R., Jalink, K., Zuker, C.S. Neuron (1998) [Pubmed]
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