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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Synaptic Transmission

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Disease relevance of Synaptic Transmission


Psychiatry related information on Synaptic Transmission


High impact information on Synaptic Transmission


Chemical compound and disease context of Synaptic Transmission


Biological context of Synaptic Transmission


Anatomical context of Synaptic Transmission


Associations of Synaptic Transmission with chemical compounds

  • AMPA-type glutamate receptors (AMPA-Rs) mediate a majority of excitatory synaptic transmission in the brain [31].
  • Furthermore, several lines of evidence suggest that proline may serve as a modulator of synaptic transmission in the mammalian brain [32].
  • Functional analysis of the STM7 recombinant protein corresponding to the reported 2.7-kilobase transcript has demonstrated PtdlnsP 5-kinase activity, supporting the idea that the disease is caused by a defect in the phosphoinositide pathway, possibly affecting vesicular trafficking or synaptic transmission [33].
  • The contribution of AMPA and NMDA receptors to synaptic transmission and plasticity is well established [28].
  • Opioids inhibit GABA-mediated (GABAergic) synaptic transmission in the PAG and other brain regions by reducing the probability of presynaptic neurotransmitter release, but the mechanisms involved remain uncertain [34].

Gene context of Synaptic Transmission


Analytical, diagnostic and therapeutic context of Synaptic Transmission


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