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Gene Review

how  -  held out wings

Drosophila melanogaster

Synonyms: 0904/17, 24B, CG10293, Dmel\CG10293, HOW, ...
 
 
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High impact information on how

  • who encodes a KH RNA binding protein that functions in muscle development [1].
  • Thus, the struthio gene encodes a putative RNA-binding protein that appears to regulate some aspects of Drosophila integrin functioning [2].
  • We have cloned and characterized a gene (struthio) that is expressed in embryonic mesodermal and muscle cells, including cardioblasts, and epidermal muscle attachment sites in a pattern that is reminiscent of the expression pattern of the PS integrins [2].
  • The responsible gene for hypomyelinating quaking deficiency, qkI, encoding a KH RNA binding protein, is expressed abundantly in the developing mouse nervous system, whereas who/how/struthio, a homologue of the qkI in Drosophila, is expressed predominantly in the mesoderm [3].

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