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Gene Review:

MYC - v-myc myelocytomatosis viral oncogene...

Sus scrofa

Shi, Y. et al., Reiner, G. et al., Heldin, N.E. et al., Reiner, G. et al.

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High impact information on MYC

We have previously demonstrated the growth-inhibitory effect of antisense oligomers targeting the c-myc proto-oncogene in human smooth muscle cells [1].
(3) It is postulated that the c-myc proto-oncogene is involved in the process of vascular remodeling, regulating smooth muscle cell proliferation and extracellular matrix synthesis [1].
An EcoRV RFLP in the porcine c-myc proto-oncogene [2].
Expression of the c-myc proto-oncogene in growth stimulated porcine thyroid follicle cells [3].

Analytical, diagnostic and therapeutic context of MYC

Four PCR-RFLPs and a sequence polymorphism in the porcine c-myc proto-oncogene and confirmation of the chromosomal localisation on SSC4 by linkage mapping [4].

References

Transcatheter delivery of c-myc antisense oligomers reduces neointimal formation in a porcine model of coronary artery balloon injury. Shi, Y., Fard, A., Galeo, A., Hutchinson, H.G., Vermani, P., Dodge, G.R., Hall, D.J., Shaheen, F., Zalewski, A. Circulation (1994) [Pubmed]
An EcoRV RFLP in the porcine c-myc proto-oncogene. Reiner, G., Dzapo, V. Anim. Genet. (1999) [Pubmed]
Expression of the c-myc proto-oncogene in growth stimulated porcine thyroid follicle cells. Heldin, N.E., Karlsson, F.A., Westermark, B. Acta endocrinologica. Supplementum. (1987) [Pubmed]
Four PCR-RFLPs and a sequence polymorphism in the porcine c-myc proto-oncogene and confirmation of the chromosomal localisation on SSC4 by linkage mapping. Reiner, G., Willems, H., Geldermann, H., Dzapo, V. Anim. Genet. (2000) [Pubmed]

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