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Gene Review

SOD1  -  superoxide dismutase 1, soluble

Pan troglodytes

 
 
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Analytical, diagnostic and therapeutic context of SOD1

  • Southern blotting showed that the SOD1 gene is modified in the three orangutans that were investigated and that a further modification of the 5'-end of the gene had occurred in Ralfina [1].
  • In situ hybridization of the SOD1 cDNA human probe showed a heterozygous intra-chromosomal rearrangement of pair PPY XXI, possibly an insertion, in Ralfina [1].

References

  1. Increased SOD1 enzymatic activity and gene modifications in orangutans: evolutionary implications. de Grouchy, J., Nicole, A., Cochet, C., Sinet, P.M., Créau-Goldberg, N. Hum. Genet. (1991) [Pubmed]
 
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