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Gene Review

SOD1  -  superoxide dismutase 1, soluble

Macaca mulatta

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Disease relevance of SOD1


High impact information on SOD1


Associations of SOD1 with chemical compounds

  • Single- and double-label immunohistochemical experiments were carried out using antibodies against the enzymes copper, zinc superoxide dismutase (SOD1), or manganese superoxide dismutase (SOD2), and against markers of various striatal cell types [3].


  1. Antisense oligonucleotide therapy for neurodegenerative disease. Smith, R.A., Miller, T.M., Yamanaka, K., Monia, B.P., Condon, T.P., Hung, G., Lobsiger, C.S., Ward, C.M., McAlonis-Downes, M., Wei, H., Wancewicz, E.V., Bennett, C.F., Cleveland, D.W. J. Clin. Invest. (2006) [Pubmed]
  2. Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Pardo, C.A., Xu, Z., Borchelt, D.R., Price, D.L., Sisodia, S.S., Cleveland, D.W. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  3. Differential abundance of superoxide dismutase in interneurons versus projection neurons and in matrix versus striosome neurons in monkey striatum. Medina, L., Figueredo-Cardenas, G., Reiner, A. Brain Res. (1996) [Pubmed]
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